Hussein, E., Ismail, M., Galal, A., Fathy, A. (2020). Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery. The Egyptian Journal of Hospital Medicine, 81(4), 1866-1871. doi: 10.21608/ejhm.2020.121013
Emad El-dien Ahmed Hussein; Mohammed Ahmed Mohammed Ismail; Ali Mahmoud Mohammed Galal; Ahmed Khalf Fathy. "Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery". The Egyptian Journal of Hospital Medicine, 81, 4, 2020, 1866-1871. doi: 10.21608/ejhm.2020.121013
Hussein, E., Ismail, M., Galal, A., Fathy, A. (2020). 'Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery', The Egyptian Journal of Hospital Medicine, 81(4), pp. 1866-1871. doi: 10.21608/ejhm.2020.121013
Hussein, E., Ismail, M., Galal, A., Fathy, A. Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery. The Egyptian Journal of Hospital Medicine, 2020; 81(4): 1866-1871. doi: 10.21608/ejhm.2020.121013
Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery
Background: Atherosclerotic peripheral artery disease (PAD) affects a growing number of patients in aging populations. Peripheral artery disease (PAD) accounts for a large proportion of cardiovascular disease (CVD) prevalence in most world regions. Objective: This study aims to evaluate and compare the patency, clinical outcome, and limb salvage rates between the simple percutaneous Transluminal angioplasty and the drug-coated balloons in chronic total occlusion of the femoropopliteal arterial segment on the short-term course. Patients and Method: A prospective randomized controlled comparative study was conducted in the vascular surgery department; Aswan University Hospital during the period from March 2018 to March 2020. In total, 30 patients with a well-established diagnosis of superficial femoral artery (SFA) and/or proximal popliteal lesions with symptoms of PAD. Results: The primary patency at 12-month following treatment with DCB was significantly better 100. %, 80.0%, 60.0% at 1, 6, 12 months compared with POBA 86.7 %, 66.7%, 46.7% at 1, 6, 12 months. The rate of clinically- driven TLR was the same in both groups (26.6%). The use of DCB was safe and did not increase the major adverse clinical events (death, myocardial infarction, and minor or major amputation) when compared with those seen with the use of the uncoated balloons). Conclusion: Use of DCBs is associated with improved vessel patency when compared to POBA in patients with FPD. There was no difference in clinically driven TLR between DCB and POBA in our study.
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