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Fatahi, D., Al Asmari, A., Bukhari, G., Alshamrani, H., Hunaydi, K., Sharahili, A., Alharshan, T., Alherz, A. (2018). Crohn’s Disease: Pathophysiology, and Management. The Egyptian Journal of Hospital Medicine, 70(11), 2004-2007. doi: 10.21608/ejhm.2018.9407
Dima Ammar Fatahi; Abdullah Saad Al Asmari; Ghadah Abdulrahman Bukhari; Homoud Abdulaziz Alshamrani; Khalid Abdullah Hunaydi; Ahmad Mufarreh Sharahili; Tahani Khalid Alharshan; Anhar Ali Alherz. "Crohn’s Disease: Pathophysiology, and Management". The Egyptian Journal of Hospital Medicine, 70, 11, 2018, 2004-2007. doi: 10.21608/ejhm.2018.9407
Fatahi, D., Al Asmari, A., Bukhari, G., Alshamrani, H., Hunaydi, K., Sharahili, A., Alharshan, T., Alherz, A. (2018). 'Crohn’s Disease: Pathophysiology, and Management', The Egyptian Journal of Hospital Medicine, 70(11), pp. 2004-2007. doi: 10.21608/ejhm.2018.9407
Fatahi, D., Al Asmari, A., Bukhari, G., Alshamrani, H., Hunaydi, K., Sharahili, A., Alharshan, T., Alherz, A. Crohn’s Disease: Pathophysiology, and Management. The Egyptian Journal of Hospital Medicine, 2018; 70(11): 2004-2007. doi: 10.21608/ejhm.2018.9407

Crohn’s Disease: Pathophysiology, and Management

Article 24, Volume 70, Issue 11, January 2018, Page 2004-2007  XML PDF (248.12 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2018.9407
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Authors
Dima Ammar Fatahi email 1; Abdullah Saad Al Asmari2; Ghadah Abdulrahman Bukhari3; Homoud Abdulaziz Alshamrani4; Khalid Abdullah Hunaydi5; Ahmad Mufarreh Sharahili5; Tahani Khalid Alharshan6; Anhar Ali Alherz7
1Tishreen University
2Taif University
3Ibn Sina National College
4Primary Health Care Center, Riyadh
5Aseer Central Hospital
6King Faisal University
7King Faisal General Hospital
Abstract
Background: The incidence of crohn’s disease reaches up to 20 per 100,000 people per year, with a median age of 30 years, and is higher in the developed world. Although the exact cause and pathophysiology is unknown, several environmental and genetic factors have been linked with higher risk or severity of the disease.
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: crohn’s disease, inflammatory bowel disease, genetics of crohn’s disease, diagnosis of IBD, management crohn’s disease
Aim of the study: In this review, we aim to study the pathophysiology, diagnosis and management of crohn’s disease. We will pay special attention to the newer biological drugs used in management.    
Conclusion: Crohn’s disease is usually managed with medical treatment, although many patients will need to undergo surgery at least once. Treatment usually aims at the induction and maintenance of a remission without the excessive use and dependence of steroids. Achieving higher quality of life is the main goal of any modality of treatment.
Keywords
Crohn’s disease; inflammatory bowel disease; medical management for crohn’s disease
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