(2025). Vitamin D Deficiency and Its Association with Metabolic Syndrome in Egyptian Patients with Psoriatic Arthritis. The Egyptian Journal of Hospital Medicine, 98(1), 88-95. doi: 10.21608/ejhm.2025.401104
. "Vitamin D Deficiency and Its Association with Metabolic Syndrome in Egyptian Patients with Psoriatic Arthritis". The Egyptian Journal of Hospital Medicine, 98, 1, 2025, 88-95. doi: 10.21608/ejhm.2025.401104
(2025). 'Vitamin D Deficiency and Its Association with Metabolic Syndrome in Egyptian Patients with Psoriatic Arthritis', The Egyptian Journal of Hospital Medicine, 98(1), pp. 88-95. doi: 10.21608/ejhm.2025.401104
Vitamin D Deficiency and Its Association with Metabolic Syndrome in Egyptian Patients with Psoriatic Arthritis. The Egyptian Journal of Hospital Medicine, 2025; 98(1): 88-95. doi: 10.21608/ejhm.2025.401104
Vitamin D Deficiency and Its Association with Metabolic Syndrome in Egyptian Patients with Psoriatic Arthritis
Background: Vitamin D (Vit D) deficiency has been implicated in several autoimmune diseases, including psoriatic arthritis (PsA), and is considered a potential risk factor for metabolic syndrome (MetS). Objective: This study aimed to investigate the prevalence of Vit D deficiency and its association with MetS components in Egyptian patients with PsA. Patients and methods: In this cross-sectional study, 60 PsA patients were recruited from Tanta University Hospitals and evaluated for MetS according to established criteria. Vit D levels were measured using a CLIA kit, and disease activity was assessed via the disease activity in psoriatic arthritis "DAPSA" score. Results: Among the 60 patients, 58.3% (35) met the criteria for MetS. Vit D deficiency (<10 ng/ml) was present in 43.3% of patients, with a significantly higher prevalence in the MetS group (54.3%) than in non-MetS patients (28%, p=0.027). Vit D levels showed a strong negative correlation with waist circumference (rs = -0.606, p < 0.001), BMI (rs = -0.552, p = 0.001), and fasting glucose (rs = -0.867, p < 0.001). Logistic regression identified Vit D deficiency as a significant risk factor for MetS (OR = 1.078, 95% CI = 1.016-1.143, p = 0.012). Conclusion: It could be concluded that Vit D deficiency is prevalent among PsA patients and is significantly associated with MetS risk. Addressing Vit D deficiency may be essential in managing metabolic health in PsA patients.
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