Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters

Helal, Eman G.E.; Abd-El-Aziz, Mohamed A.; Ahmed, Shaimaa S.

doi:10.21608/ejhm.2019.29114

Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters

Document Type : Original Article

Authors

¹ Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt

² Physiology Department, Faculty of Medicine, Al-Azhar University (Boys), Cairo, Egypt

³ Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt.

10.21608/ejhm.2019.29114

Abstract

Background: Phytoestrogen is a plant derived compound which have estrogenic effect similar to estrogen. Aim of work: The present study was carried out to investigate some pharmacological and biochemical effects of anise oil on male albino rats. Materials and methods: twelve animals were divided randomly into two groups. Group A: Control. Group B: treated rats. The treated rats were given an oral dose of 1 ml/kg body weight/day anise oil once daily for one month. At the end of the experiment, blood samples were collected for biochemical analysis. Results: The anise oil induced highly significant decrease (p<0.01) in TC, TG, LDL, VLDL, LDL/HDL. In addition, significant increase (p<0.05) in HDL and highly significantly decreased in FSH, LH, testosterone and sperm count compared to normal control group. Conclusion: This study showed that high levels of anise intake cause hormonal disturbance and decrease sperm count.

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