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Helal, E., Abd-El-Aziz, M., Ahmed, S. (2019). Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters. The Egyptian Journal of Hospital Medicine, 75(1), 1918-1922. doi: 10.21608/ejhm.2019.29114
Eman G.E. Helal; Mohamed A. Abd-El-Aziz; Shaimaa S. Ahmed. "Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters". The Egyptian Journal of Hospital Medicine, 75, 1, 2019, 1918-1922. doi: 10.21608/ejhm.2019.29114
Helal, E., Abd-El-Aziz, M., Ahmed, S. (2019). 'Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters', The Egyptian Journal of Hospital Medicine, 75(1), pp. 1918-1922. doi: 10.21608/ejhm.2019.29114
Helal, E., Abd-El-Aziz, M., Ahmed, S. Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters. The Egyptian Journal of Hospital Medicine, 2019; 75(1): 1918-1922. doi: 10.21608/ejhm.2019.29114

Effect of Anise (Pimpinella Anisum L.) as Phytoestrogen on Some Sex Hormones and Biochemical Parameters

Article 3, Volume 75, Issue 1, April 2019, Page 1918-1922  XML PDF (459.14 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.29114
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Authors
Eman G.E. Helal email orcid 1; Mohamed A. Abd-El-Aziz2; Shaimaa S. Ahmed3
1Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt
2Physiology Department, Faculty of Medicine, Al-Azhar University (Boys), Cairo, Egypt
3Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt.
Abstract
Background: Phytoestrogen is a plant derived compound which have estrogenic effect similar to estrogen. Aim of work: The present study was carried out to investigate some pharmacological and biochemical effects of anise oil on male albino rats. Materials and methods: twelve animals were divided randomly into two groups. Group A: Control. Group B: treated rats. The treated rats were given an oral dose of 1 ml/kg body weight/day anise oil once daily for one month. At the end of the experiment, blood samples were collected for biochemical analysis. Results: The anise oil induced highly significant decrease (p<0.01) in TC, TG, LDL, VLDL, LDL/HDL. In addition, significant increase (p<0.05) in HDL and highly significantly decreased in FSH, LH, testosterone and sperm count compared to normal control group. Conclusion: This study showed that high levels of anise intake cause hormonal disturbance and decrease sperm count.
Keywords
Anise oil; Lipid profile; albino rats; Sperm count; physiological parameters
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