Ali, A., Elsayed, Y., Saad, H., Elkataway, A. (2022). Prediction and Prevention of Pre-eclampsia by Measuring Mean Platelet Volume and Uterine Artery Doppler Indices in High-Risk Pregnant Women. The Egyptian Journal of Hospital Medicine, 88(1), 2319-2324. doi: 10.21608/ejhm.2022.235955
Ali El-Shabrawy Ali; Youssef Abo Elwan Elsayed; Hana Matoog Dawo Saad; Ahmed Metwally Elkataway. "Prediction and Prevention of Pre-eclampsia by Measuring Mean Platelet Volume and Uterine Artery Doppler Indices in High-Risk Pregnant Women". The Egyptian Journal of Hospital Medicine, 88, 1, 2022, 2319-2324. doi: 10.21608/ejhm.2022.235955
Ali, A., Elsayed, Y., Saad, H., Elkataway, A. (2022). 'Prediction and Prevention of Pre-eclampsia by Measuring Mean Platelet Volume and Uterine Artery Doppler Indices in High-Risk Pregnant Women', The Egyptian Journal of Hospital Medicine, 88(1), pp. 2319-2324. doi: 10.21608/ejhm.2022.235955
Ali, A., Elsayed, Y., Saad, H., Elkataway, A. Prediction and Prevention of Pre-eclampsia by Measuring Mean Platelet Volume and Uterine Artery Doppler Indices in High-Risk Pregnant Women. The Egyptian Journal of Hospital Medicine, 2022; 88(1): 2319-2324. doi: 10.21608/ejhm.2022.235955
Prediction and Prevention of Pre-eclampsia by Measuring Mean Platelet Volume and Uterine Artery Doppler Indices in High-Risk Pregnant Women
Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Sharkia, Egypt
Abstract
Background: Pre-eclampsia (PE) is a multisystem disorder of unknown cause that is unique to human pregnancy. Objective: This work aimed to evaluate platelet volume and its significance in the prediction of preeclampsia. Methods: This is a prospective cohort study that was carried out in the Obstetrics and Gynecology Department (High-risk unit) at Zagazig University Hospitals. Sixty high-risk pregnant women were involved during the period from July 2021 to February 2022. Ultrasound scanning was done to evaluate fetal biometric parameters according to fetal morphology and localization of the placenta. The uterine arteries were identified, and the pulsatility index and resistive index were measured bilaterally. Ultrasound examinations were performed by one observer only. Results: Platelet (PLT) was significantly higher among control and unaffected groups at all times but MPV and PDW were significantly higher among cases at all times. The first, second, third, fourth, and fifth visits were at 12, 14, 16, 18, and 20 weeks gestation respectively Conclusions Abnormal platelet indices and uterine artery Doppler indices can be considered as an early, economical, and rapid procedure for the assessment of PE.