Sensorineural Hearing Affection In Sickle Cell Disease Patients With Chronic Renal Failure Under Dialysis

Document Type : Original Article

Authors

1 Lecturer of internal med & nephrology Ain-Shams university

2 Fellow of nepnrology , Ahamed Maher Teaching Hospital

3 assistant professor Of internal med &immunology Al-Azhar university

4 lecturer of E.N.T. Ain shams university.

Abstract

Objective: to study the problem of hearing loss in patients of chronic renal failure on regular haemodialysis and The factors which affect it. And to study the effect of sickle cell disease on hearing loss. we studied hearing loss in dialysis patients, sickle cell disease patients and patients of sickle cell disease with chronic renal failure under dialysis compared to normal control subjects.
Design: !          "  " include sickle cell disease patients with chronic renal fa    "  #$ % &  '" include  (# #      "  #$ % &  '"    (# )     &  ' " include the normal   *+ & *+ '
All groups are subjected to full history, thorough clinical examination including neurological and ENT examination, investigations includes Hb, s. creatinine, s.albumen, s.calcium and calculation of kt/v for dialysis patients. Full audiological assessment, using # ,-GSI audiometer was done for all groups with special concentration at frequency of - .
Results: hearing loss was found in patients with chronic renal failure more than normal control. Patient with sickle cell disease have hearing disorders significantly higher than  $    /%  - . % 0 (##      ) cell disease have significantly.
Marked degree of SNHL than those with SCD only. Hearing loss in patients with
12    (# * 3 &4!4! ' # "  # "  
patients with chronic renal failure with or without SCD correlate with duration of dialysis , presence of peripheral neuropathy, s. calcium level, efficiency of dialysis marked by kt/v.
Conclusion and recommendation: hearing disorder is common in patients with chronic renal failure under regular haemodialysis and it increase with duration of dialysis it should be suspected if there is Peripheral neuropathy. It can be reduced with efficient dialysis, correction of anemia, adjustment of calcium level. Patients with SCD suffer also some degree of hearing loss especially at higher frequency and this degree of hearing loss

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