Home Articles List Article Information
The Egyptian Journal of Hospital Medicine
Journal Archive
Volume Volume 97 (2024)
Volume Volume 96 (2024)
Volume Volume 95 (2024)
Volume Volume 94 (2024)
Volume Volume 93 (2023)
Volume Volume 92 (2023)
Volume Volume 91 (2023)
Volume Volume 90 (2023)
Volume Volume 89 (2022)
Volume Volume 88 (2022)
Volume Volume 87 (2022)
Volume Volume 86 (2022)
Volume Volume 85 (2021)
Volume Volume 84 (2021)
Volume Volume 83 (2021)
Volume Volume 82 (2021)
Volume Volume 81 (2020)
Volume Volume 80 (2020)
Volume Volume 79 (2020)
Volume Volume 78 (2020)
Volume Volume 77 (2019)
Volume Volume 76 (2019)
Volume Volume 75 (2019)
Volume Volume 74 (2019)
Volume Volume 73 (2018)
Volume Volume 72 (2018)
Volume Volume 71 (2018)
Volume Volume 70 (2018)
Volume Volume 69 (2017)
Volume Volume 68 (2017)
Volume Volume 67 (2017)
Volume Volume 66 (2017)
Volume Volume 65 (2016)
Volume Volume 64 (2016)
Volume Volume 63 (2016)
Volume Volume 62 (2016)
Volume Volume 61 (2015)
Volume Volume 60 (2015)
Volume Volume 59 (2015)
Volume Volume 58 (2015)
Volume Volume 57 (2014)
Volume Volume 56 (2014)
Volume Volume 55 (2014)
Volume Volume 54 (2014)
Volume Volume 53 (2013)
Volume Volume 52 (2013)
Volume Volume 51 (2013)
Volume Volume 50 (2013)
Volume Volume 49 (2012)
Volume Volume 48 (2012)
Volume Volume 47 (2012)
Volume Volume 46 (2012)
Volume Volume 45 (2011)
Volume Volume 44 (2011)
Volume Volume 43 (2011)
Volume Volume 42 (2011)
Volume Volume 41 (2010)
Volume Volume 40 (2010)
Volume Volume 39 (2010)
Volume Volume 38 (2010)
Volume Volume 37 (2009)
Volume Volume 36 (2009)
Volume Volume 35 (2009)
Volume Volume 34 (2009)
Volume Volume 33 (2008)
Volume Volume 32 (2008)
Volume Volume 31 (2008)
Volume Volume 30 (2008)
Volume Volume 29 (2007)
Volume Volume 28 (2007)
Volume Volume 27 (2007)
Volume Volume 26 (2007)
Volume Volume 25 (2006)
Volume Volume 24 (2006)
Volume Volume 23 (2006)
Volume Volume 22 (2006)
Volume Volume 21 (2005)
Volume Volume 20 (2005)
Volume Volume 19 (2005)
Volume Volume 18 (2005)
Volume Volume 17 (2004)
Volume Volume 16 (2004)
Volume Volume 15 (2004)
Volume Volume 14 (2004)
Volume Volume 13 (2003)
Volume Volume 12 (2003)
Volume Volume 11 (2003)
Volume Volume 10 (2003)
Volume Volume 9 (2002)
Volume Volume 8 (2002)
Volume Volume 7 (2002)
Volume Volume 6 (2002)
Volume Volume 5 (2001)
Volume Volume 4 (2001)
Volume Volume 3 (2001)
Volume Volume 2 (2001)
Volume Volume 1 (2000)
Al-Shaibani, E., Ismail, N., Eissa, O., Rady, M., Zaki, Z. (2009). Teratological Effects of Gamma-Irradiation during three Gestaional Intervals in Rats. The Egyptian Journal of Hospital Medicine, 36(1), 456-467. doi: 10.21608/ejhm.2009.17528
Elham A. Al-Shaibani; Nadia, H. Ismail; Omaima S. Eissa; Mohamed I. Rady; Zaki, T. Zaki. "Teratological Effects of Gamma-Irradiation during three Gestaional Intervals in Rats". The Egyptian Journal of Hospital Medicine, 36, 1, 2009, 456-467. doi: 10.21608/ejhm.2009.17528
Al-Shaibani, E., Ismail, N., Eissa, O., Rady, M., Zaki, Z. (2009). 'Teratological Effects of Gamma-Irradiation during three Gestaional Intervals in Rats', The Egyptian Journal of Hospital Medicine, 36(1), pp. 456-467. doi: 10.21608/ejhm.2009.17528
Al-Shaibani, E., Ismail, N., Eissa, O., Rady, M., Zaki, Z. Teratological Effects of Gamma-Irradiation during three Gestaional Intervals in Rats. The Egyptian Journal of Hospital Medicine, 2009; 36(1): 456-467. doi: 10.21608/ejhm.2009.17528

Teratological Effects of Gamma-Irradiation during three Gestaional Intervals in Rats

Article 7, Volume 36, Issue 1, July 2009, Page 456-467  XML PDF (392.53 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2009.17528
View on SCiNiTO View on SCiNiTO
Authors
Elham A. Al-Shaibani1; Nadia, H. Ismail2; Omaima S. Eissa3; Mohamed I. Rady3; Zaki, T. Zaki3
1Department of Biology- Faculty of Science, Sana'a University
2Department of Zoology, Faculty of Grils, Ain Shams University
3Radiation Biology Dept., National Center for Radiation Research and Technology, Atomic Energy Authority and Department of Zoology, Faculty of Science, Al-Azhar University
Abstract
Aim of the work: The present study aimed to evaluate the teratological effects of gamma-irradiation during three intervals of gestation; pre-implantation, organogenesis and fetal periods in rats.
Material and methods: Four groups of pregnant rats were used in this study; the first one (GI) served as control. The second (GII), third (GIII) and fourth (GIV) groups were subjected to whole body γ-radiation at a sub-lethal single dose level of 4 Gy at the third day, 10th day and 14th day of gestation respectively.Pregnant rats were sacrificed at the 20th day of gestation, implantation sites, resorption, embryonic death, fetal death, growth retarded fetuses, external malformations and skeletal malformation were recorded.
Results: The results showed that whole body γ-irradiation caused resorption in the embryos of pregnant rats especially in those exposed during the pre-implantation period than the two other periods. The embryonic and fetal deaths were prominent in the fetuses maternally exposed to whole body γ-irradiation during the organogenesis period. The highest percentage of growth retarded fetuses was found in fetuses maternally exposed to γ-rays during the organogenesis period followed by fetuses maternally exposed to γ-irradiation during the fetal period and then fetuses maternally exposed to γ-irradiation during the pre-implantation period. The skeletal malformations as a result of γ-irradiation were mostly represented in less ossification in the skull bones, less ossification in the vertebral centra and wavy ribs. The most affected fetal skeleton was perceptive in GIII (fetuses maternally exposed to γ-irradiation during the organogenesis period) followed by GII and then GIV.
 
Keywords
γ-irradiation; pregnant rats; Teratology
Statistics
Article View: 168
PDF Download: 447