Detection of Visceral adiposity by Ultrasonography and its relation to insulin resistance in HCV patients

Mohamed, Mostafa K.; Esmat, Gamal; Said, Mohamed; Abdel- Hamid, Mohamed; Hassany, Mohamed; Hassanein, Mohamad A.; El- Atrebi, Kamal A.

doi:10.21608/ejhm.2010.16954

Detection of Visceral adiposity by Ultrasonography and its relation to insulin resistance in HCV patients

Document Type : Original Article

Authors

¹ Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University.

² Department of Tropical Medicine, Cairo University.

³ Viral Hepatitis Research Laboratory, National Hepatology and Tropical Medicine Research Institute

⁴ Department of Tropical Medicine, National Hepatology and Tropical Medicine Research Institute.

10.21608/ejhm.2010.16954

Abstract

Background:HepatitisCisamajorcauseofliver-relatedmorbidityandmortalityandrepresentsa majorpublichealthprobleminEgyptandworldwide.Ultrasonographyisasimplenon-invasive methodfordetectionofvisceralfat,whichisdirectly,correlatedwithinsulinresistance(IR)aswellas developmentoftype2diabetesmellitus.
Aim:ToassessthevalidityofdetectionofvisceraladiposetissueareawithUltrasonographyandits correlationwithIRinHCVpatients
Materials&Method:Thestudyparticipantsweresubcategorizedintotwogroups,Group(I): included867healthysubjectswithnegative(HCV)RNAasacontrolgroup.Group(II):included277 patientswithchronicHCVasastudygroup.The2groupsweresubjectedtothoroughhistorytaking, fullclinicalexamination,Anthropometricstudy,ultrasonographicexaminationandlaboratory investigationsincludingliverfunctions,viralmarkers,andqualitativePCRforHCVRNA,lipid profile&glucoseprofile.
Results:Thisstudyrevealedthatultrasonographyisasimple,non-invasive,safemethodindetection ofvisceraladiposity,whichiscorrelatedsignificantlywithIRinchronicHCVpatients.

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