Is Neutrophil/Lymphocyte Ratio A Useful Marker to Predict the Severity of Pre-Eclampsia?

Document Type : Original Article

Authors

1 Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

2 Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Abstract

Background: Preeclampsia refers to the new onset of hypertension and proteinuria or hypertension and end-organ dysfunction with or without proteinuria after 20 weeks of gestation in a previously normotensive woman.
Objective: This study was aimed to evaluate the relationship between Neutrophil/Lymphocyte ratio (NLR) in patients with pre-eclampsia (PE) and severity of preeclampsia. Subjects and methods: This prospective study comprised a total of 150 pregnant females divided in 3 groups "50 healthy pregnant females (Group 1), 50 females with mild pre-eclampsia (Group 2) and 50 with severe pre-eclampsia (Group 3)".All the study participants were statistically compared in respect to Neutrophil/Lymphocyte Ratio (NLR) and the baseline data including age and BMI. Results: Maternal NLR was determined to be significantly high in the pre-eclamptic patients (Groups 2 and 3) compared to those with healthy pregnancies (Group 1) (p = 0.0003).NLR was significantly higher in the severe pre-eclampsia group than in the mild pre-eclampsia group (p = 0.042). Conclusion: It could be concluded that while NLR was determined as significantly high in patients with pre- eclampsia, to be able to use this in the classification of the severity of pre-eclampsia, there is a need for further studies on a more extensive population.

Keywords

The Egyptian Journal of Hospital Medicine
Volume 73, Issue 5
October 2018
Pages 6621-6625

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