Fecal Calprotectin Level in Term and Preterm Babies before and after Starting of Feeding

Romih, Mohammed Mahmoud; El-hindawy, Eman M. M.; Khalifaa, Naglaa Ali; Othman, Ahmed Mohammed

doi:10.21608/ejhm.2021.152998

Fecal Calprotectin Level in Term and Preterm Babies before and after Starting of Feeding

Document Type : Original Article

Authors

10.21608/ejhm.2021.152998

Abstract

Background: Fecal biomarkers (FCP) may be characterized by a superior diagnostic sensitivity as they are highly organ specific. Fecal calprotectin meets the criteria of a laboratory parameter suitable for the assessment of inflammatory bowel disease. Objective: To evaluate FCP levels in both preterm and full-term infants after start feeding and its relationship with the type of feeding, birth weight, and other clinical and laboratory parameters.
Patients and Methods: This study was carried out at the outpatient clinic of the Pediatric Department Zagazig University Hospitals on 88 infants during the period from October 2016 to October 2017.
Results: FCP levels increased in 100% of infants involved in the study after feeding. FCP levels have a wide range of variation from 82 to 425 µg/g before feeding and from 174 to 692 µg/g after feeding. A significant negative correlation between FCP levels before and after feeding with birth weight especially in the full-term group. A higher percentage of increase was observed in breastfeeding and ranged from 64.76 to 91.31%, while formula-fed feeding ranged from 39.09 to 84.94%.
Conclusion: FCP levels increased in all infants after feeding with a wide range of variations with no differences between infants born vaginally or with C-section. The FCP levels increased significantly with breastfeeding than formula-fed feeding.

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