Elsayed, H., Ibrahim, M., El Safty, M., Salim, S. (2017). 1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy. The Egyptian Journal of Hospital Medicine, 68(3), 1527-1532. doi: 10.12816/0039699
Helmy M. Elsayed; Mohammed EM. Ibrahim; Mohammed SL El Safty; Samar MM Salim. "1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy". The Egyptian Journal of Hospital Medicine, 68, 3, 2017, 1527-1532. doi: 10.12816/0039699
Elsayed, H., Ibrahim, M., El Safty, M., Salim, S. (2017). '1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy', The Egyptian Journal of Hospital Medicine, 68(3), pp. 1527-1532. doi: 10.12816/0039699
Elsayed, H., Ibrahim, M., El Safty, M., Salim, S. 1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy. The Egyptian Journal of Hospital Medicine, 2017; 68(3): 1527-1532. doi: 10.12816/0039699
1,5 Anhydroglucitol Evaluation as Glycemic Control Parameter of Diabetes Mellitus in Pregnancy
Department of Obstetrics and Gynecology,Faculty of Medicine, Ain Shams University
Abstract
Background: 1,5-Anhydroglucitol (1,5-AG) provides a reliable opportunity to assess the frequency and extent of intermittent hyperglycemic episodes. Aim of the Work: this study aimed to evaluate an alternative parameter to monitor blood glucose in pregnancies complicated with diabetes mellitus by studying the relationship between 1,5 Anhydroglucitol and self-monitoring of blood glucose level in pregnant women complicated with diabetes mellitus. Patients and Methods: this cross-sectional study with retrospective data was conducted on seventy pregnant women known to have pre-gestational or gestational diabetes mellitus attending Ain Shams University Maternity Hospital fulfilling the inclusion criteria of pre-gestational or gestational diabetes mellitus according to the criteria of the American Diabetes Association. Results: this study revealed a highly significant negative correlation between MMG (mean maximum glycemia) and 1,5 AG (r: -0.817, p-value: <0.001), also pre prandial blood glucose level (r: -0.500, p-value: <0.001) and a negative correlation and highly significant was found between post prandial blood glucose level and 1,5 AG (r: -0.640, p-value: <0.001). Conclusion: 1,5-AG is better than HbA1c as a tool for monitoring the glucose profile in pregnancies complicated by diabetes mellitus especially for the hyperglycemic episodes. Recommendations: as majority of interpretations for utility of 1,5-AG in pregnancy are based on scanty few clinical data so there is a scope of potential possibilities for its use in pregnancy and continuous research may allow its new applications and usefulness in pregnancy in the future.
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