Ragb, T., Saad, A., Abd Elaal, M., Yassin, A., Rashed, A. (2017). The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients. The Egyptian Journal of Hospital Medicine, 68(1), 1059-1068. doi: 10.12816/0038209
Tamer Mohamed Ragb; Ahmad AlaaEldin Ahmad Saad; Moneir Osman Amin Abd Elaal; Abdellah Nazeer Yassin; ALSayed Mohamed Rashed. "The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients". The Egyptian Journal of Hospital Medicine, 68, 1, 2017, 1059-1068. doi: 10.12816/0038209
Ragb, T., Saad, A., Abd Elaal, M., Yassin, A., Rashed, A. (2017). 'The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients', The Egyptian Journal of Hospital Medicine, 68(1), pp. 1059-1068. doi: 10.12816/0038209
Ragb, T., Saad, A., Abd Elaal, M., Yassin, A., Rashed, A. The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients. The Egyptian Journal of Hospital Medicine, 2017; 68(1): 1059-1068. doi: 10.12816/0038209
The Relationship between Abdominal Aortic Calcification and Cardiac Abnormalities in Hemodialysis Patients
1Departments of Internal medicine Faculty of Medicine, Al Azhar university, Cairo, Egypt
2Departments of Internal CardiologyFaculty of Medicine, Al Azhar university, Cairo, Egypt
3Departments of Internal RadiologyFaculty of Medicine, Al Azhar university, Cairo, Egypt
Abstract
Background: Abdominal aortic calcification (AAC) is a marker of subclinical atherosclerotic disease and an independent predictor of subsequent vascular morbidity and mortality. Aim of the work: This study was conducted to investigate the association of abdominal aortic calcification with cardiac abnormalitiesin hemodialysispatient (HD). Methods: This cross-sectionalobservational study wasperformed on 90 patients (50 males and 40 females)with chronic kidney disease, stage 5 (CKD)of varying etiologies from hemodialysis unit at Al-Hussein UniversityHospital. They wereundergoing regularhemodialysis for more than 6 monthes.Laboratory investigations were done including liver function tests, kidney function tests,complete blood count (CBC),C-reactive protein (CRP), fasting and random blood glucose,lipid profile, calcium, phosphorus,calcium phosphate productandparathormone(PTH).In addition, Echocardiography and X-ray plain radiography were determined. Results: Out of 90 HD patients, 37 patients (41.1 %) had valvular calcification, all of them (41.1 %) had aortic valve calcifications and AAC score exceeded 6. Only 7 patients (7.8%)had mitral valve calcifications. Moreover, cases with mitral valve calcifications had aortic valve calcification and AAC score above 12. Seven patients (7.8 %) had mildaortic regurgitation (AR)and 4 patients (4.44%) had aortic stenosis.
Conclusion: AAC precedes the occurrence of cardiac abnormalities in HD patients and has been shown to have significant prognostic significance for cardiovascular events and mortality.
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