Alzaidi, M., Almir, H., Khormi, A., Alltaleb, Y., Al Muwais, Z., Alsaleh, R., Alsaud, N., Alomar, L., Shabkah, R., Khormi, A., Safi, R. (2017). Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article. The Egyptian Journal of Hospital Medicine, 69(6), 2627-2631. doi: 10.12816/0042239
Marah Mohammed Alzaidi; Hassan Hamza A Almir; Afraa Qasim Ibrahim Khormi; Yassmeen Mohammed Alltaleb; Zahra Mohamed A Al Muwais; Rehab Abdul Rahman Alsaleh; Nora Faisal Alsaud; Lama Mohammed Alomar; Reema Adnan Shabkah; Abdulrahman Hassan Khormi; Reyhana Safi. "Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article". The Egyptian Journal of Hospital Medicine, 69, 6, 2017, 2627-2631. doi: 10.12816/0042239
Alzaidi, M., Almir, H., Khormi, A., Alltaleb, Y., Al Muwais, Z., Alsaleh, R., Alsaud, N., Alomar, L., Shabkah, R., Khormi, A., Safi, R. (2017). 'Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article', The Egyptian Journal of Hospital Medicine, 69(6), pp. 2627-2631. doi: 10.12816/0042239
Alzaidi, M., Almir, H., Khormi, A., Alltaleb, Y., Al Muwais, Z., Alsaleh, R., Alsaud, N., Alomar, L., Shabkah, R., Khormi, A., Safi, R. Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article. The Egyptian Journal of Hospital Medicine, 2017; 69(6): 2627-2631. doi: 10.12816/0042239
Poly Cystic Ovarian Syndrome and Vit D Correlation with Fertility: Review Article
1Department of Obstetrics and Gynecology, Taif University, Taif
2Department of Obstetrics and Gynecology Imam Abdulrahman bin Faisal university, Dammam
3Department of Obstetrics and Gynecology, Jazan University, Jazan
4Department of Obstetrics and Gynecology, Alfaisal University, Riyadh
5Department of Obstetrics and Gynecology, Imam Abdulrahman bin Faisal university, Dammam
6Department of Obstetrics and Gynecology, Ibn Sina National College, Jeddah
7Department of Obstetrics and Gynecology, Alfaisal University
8Department of Obstetrics and Gynecology, Almaarefa College for Science and Technology, Riyadh
9Department of Obstetrics and Gynecology,King Abdulaziz University, Jeddah
10Department of Obstetrics and Gynecology,king Fahd Central Hospital, Jazan, Saudi Arabia
11Department of Obstetrics and Gynecology,Ibn Sina National College, Jeddah
Abstract
Over the past few decades, vitamin D was proposed to be highly influential on female fertility and reproductive health. Its role was extensively studied and evaluated specifically in females with polycystic ovarian syndrome. Objectives: the aim of this research was to study the correlation between vitamin D and fertility in general, and in polycystic ovarian syndrome-associated infertility in particular. Methods: we searched Cochrane Library and PubMed for articles addressing the impact and role of vitamin D in fertility issues in females with polycystic ovary disease. Specifically-related topics were carefully reviewed and analyzed to summarize their conclusive results. Results and Discussion: Vitamin D was lower in females with PCOS and vitamin D administration had increased its level, improved metabolic disturbance and shortened inter-menstrual intervals in those patients. Patients with high vitamin D levels had a better success rate of in-vitro fertilization. However, it did not affect the time to pregnancy in PCOS women. Conclusion: Vitamin D is beneficial for improving metabolic as well as reproductive functions in women with PCOS. It is also essential for successful in-vitro fertilization, and it is probably protective against endometriosis. However, results from different studies are contradictory, and still there is no solid evidence that there is a cause-effect relationship between vitamin D and fertility.
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