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Sherif, M., Mohammed, Y., Zedan, H., Kheder, M., Mohammed, A. (2017). Toxic Effect of Some Heavy Metals (Cadmium and Lead) on Thyroid Function. The Egyptian Journal of Hospital Medicine, 69(5), 2512-2515.
Magdi Mohammed Sherif; Yousuf Solyman Mohammed; Hendawy Abd El-Moaty Zedan; Mohammed Abd El-hamid Kheder; Ahmed Hassan Abd EL-Salam Mohammed. "Toxic Effect of Some Heavy Metals (Cadmium and Lead) on Thyroid Function". The Egyptian Journal of Hospital Medicine, 69, 5, 2017, 2512-2515.
Sherif, M., Mohammed, Y., Zedan, H., Kheder, M., Mohammed, A. (2017). 'Toxic Effect of Some Heavy Metals (Cadmium and Lead) on Thyroid Function', The Egyptian Journal of Hospital Medicine, 69(5), pp. 2512-2515.
Sherif, M., Mohammed, Y., Zedan, H., Kheder, M., Mohammed, A. Toxic Effect of Some Heavy Metals (Cadmium and Lead) on Thyroid Function. The Egyptian Journal of Hospital Medicine, 2017; 69(5): 2512-2515.

Toxic Effect of Some Heavy Metals (Cadmium and Lead) on Thyroid Function

Article 25, Volume 69, Issue 5, October 2017, Page 2512-2515  XML PDF (370.92 K)
Document Type: Original Article
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Authors
Magdi Mohammed Sherif1; Yousuf Solyman Mohammed1; Hendawy Abd El-Moaty Zedan2; Mohammed Abd El-hamid Kheder3; Ahmed Hassan Abd EL-Salam Mohammed1
1Department of Forensic Medicine and Clinical Toxicology
2Department of Internal Medicine, Al-Azhar University
3Department of Clinical Pathology, Al-Azhar University, Egypt
Abstract
Aim of the work: this study aimed at exploring the effects of lead and cadmium on the thyroid function of workers of welding operation are exposed to welding fumes containing various toxic metals. Subjects and Methods: the level of blood lead and cadmium was  measured  by  atomic  absorption  spectro-photometry.    Thyroid stimulating hormone, free thyroxin, free triiodothyronine in serum were estimated by enzyme immunoassay.
Results: the workers with higher level of blood lead level (BLL) (30–60) ug/dl showed high thyroid-stimulating hormone level (0.50-9)uIU/ml andno changes in free thyroxine and free triiodothyronine. No changes in free thyroxine, free triiodothyronine and Thyroid-stimulating hormone level in relation to increase in cadmium level. Conclusion: we concluded that  higher  level  of  blood  lead  may  cause  certain  damage  to  thyroid  function  leading  to subclinical hypothyroidism.
We concluded no relation between cadmium level and thyroid hormones. The smokers have higher cadmium level (0.59-9.6)ug/L.
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