The Accuracy of Three-Dimensional Ultrasound Imaging in Detection of Lip and Palate Clefts

Alshahrani, Sarah Saeed; Alshabanah, Roa Fahad; Almohayya, Tahani Saeed; Alahmari, Ebtesam Mohammed

doi:10.12816/0041534

The Accuracy of Three-Dimensional Ultrasound Imaging in Detection of Lip and Palate Clefts

Document Type : Original Article

Authors

Faculty of Medicine, King Khalid University, Abha, Saudi Arabia

10.12816/0041534

Abstract

Background: Although there is a lack of robust evidence from prospective cohort studies that supporting using 3D ultrasound, it becomes widely used in the clinical practice of obstetrics. This review aimed At evaluating the evidence assessing the accuracy of 3D ultrasound, in the detection of cleft lip and palate in different populations at different trimesters. Methods: In July 2017, we conducted a systematic search of the databases (MEDLINE, EMBASE and Science Direct databases) as demonstrated in table 1. The titles and abstracts of the detected articles were screened to exclude irrelevantly and duplicated, in addition to articles of case reports and reviews. Finally, articles were finally included in this review and subjected to data extraction and qualitative data analysis. Results: The detection rates of cleft lip ± alveolar bone cleft by 3D ultrasound imaging were found very high by many of the included studies. A range of 85%-100% detection rate of cleft lip only and cleft lip with cleft alveolus was reported by many studies. The detection rate of cleft palate with or without cleft lip varied between 50%-100%. This review revealed a detection rate of cleft lip and palate in low-risk populations ranged between 80-100%, while in high-risk populations the detection rate varied widely between 50% -100%.
Conclusion: Although there is a wealth of evidence demonstrated the high accuracy of 3D imaging in the detection of cleft lip and palate, the available studies had a poor methodology with a high risk of bias in their findings.

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