Home Articles List Article Information
The Egyptian Journal of Hospital Medicine
Journal Archive
Volume Volume 97 (2024)
Volume Volume 96 (2024)
Volume Volume 95 (2024)
Volume Volume 94 (2024)
Volume Volume 93 (2023)
Volume Volume 92 (2023)
Volume Volume 91 (2023)
Volume Volume 90 (2023)
Volume Volume 89 (2022)
Volume Volume 88 (2022)
Volume Volume 87 (2022)
Volume Volume 86 (2022)
Volume Volume 85 (2021)
Volume Volume 84 (2021)
Volume Volume 83 (2021)
Volume Volume 82 (2021)
Volume Volume 81 (2020)
Volume Volume 80 (2020)
Volume Volume 79 (2020)
Volume Volume 78 (2020)
Volume Volume 77 (2019)
Volume Volume 76 (2019)
Volume Volume 75 (2019)
Volume Volume 74 (2019)
Volume Volume 73 (2018)
Volume Volume 72 (2018)
Volume Volume 71 (2018)
Volume Volume 70 (2018)
Volume Volume 69 (2017)
Volume Volume 68 (2017)
Volume Volume 67 (2017)
Volume Volume 66 (2017)
Volume Volume 65 (2016)
Volume Volume 64 (2016)
Volume Volume 63 (2016)
Volume Volume 62 (2016)
Volume Volume 61 (2015)
Volume Volume 60 (2015)
Volume Volume 59 (2015)
Volume Volume 58 (2015)
Volume Volume 57 (2014)
Volume Volume 56 (2014)
Volume Volume 55 (2014)
Volume Volume 54 (2014)
Volume Volume 53 (2013)
Volume Volume 52 (2013)
Volume Volume 51 (2013)
Volume Volume 50 (2013)
Volume Volume 49 (2012)
Volume Volume 48 (2012)
Volume Volume 47 (2012)
Volume Volume 46 (2012)
Volume Volume 45 (2011)
Volume Volume 44 (2011)
Volume Volume 43 (2011)
Volume Volume 42 (2011)
Volume Volume 41 (2010)
Volume Volume 40 (2010)
Volume Volume 39 (2010)
Volume Volume 38 (2010)
Volume Volume 37 (2009)
Volume Volume 36 (2009)
Volume Volume 35 (2009)
Volume Volume 34 (2009)
Volume Volume 33 (2008)
Volume Volume 32 (2008)
Volume Volume 31 (2008)
Volume Volume 30 (2008)
Volume Volume 29 (2007)
Volume Volume 28 (2007)
Volume Volume 27 (2007)
Volume Volume 26 (2007)
Volume Volume 25 (2006)
Volume Volume 24 (2006)
Volume Volume 23 (2006)
Volume Volume 22 (2006)
Volume Volume 21 (2005)
Volume Volume 20 (2005)
Volume Volume 19 (2005)
Volume Volume 18 (2005)
Volume Volume 17 (2004)
Volume Volume 16 (2004)
Volume Volume 15 (2004)
Volume Volume 14 (2004)
Volume Volume 13 (2003)
Volume Volume 12 (2003)
Volume Volume 11 (2003)
Volume Volume 10 (2003)
Volume Volume 9 (2002)
Volume Volume 8 (2002)
Volume Volume 7 (2002)
Volume Volume 6 (2002)
Volume Volume 5 (2001)
Volume Volume 4 (2001)
Volume Volume 3 (2001)
Volume Volume 2 (2001)
Volume Volume 1 (2000)
MM, E., AA, S. (2017). The Ameliorative Effect of Cleome droserifolia (Samwa) on Myocardial Injury Associated with Diabetes in Male Rats. The Egyptian Journal of Hospital Medicine, 69(4), 2222-2231. doi: 10.12816/0041521
El-Komy MM; Serag MH and Emsalam AA. "The Ameliorative Effect of Cleome droserifolia (Samwa) on Myocardial Injury Associated with Diabetes in Male Rats". The Egyptian Journal of Hospital Medicine, 69, 4, 2017, 2222-2231. doi: 10.12816/0041521
MM, E., AA, S. (2017). 'The Ameliorative Effect of Cleome droserifolia (Samwa) on Myocardial Injury Associated with Diabetes in Male Rats', The Egyptian Journal of Hospital Medicine, 69(4), pp. 2222-2231. doi: 10.12816/0041521
MM, E., AA, S. The Ameliorative Effect of Cleome droserifolia (Samwa) on Myocardial Injury Associated with Diabetes in Male Rats. The Egyptian Journal of Hospital Medicine, 2017; 69(4): 2222-2231. doi: 10.12816/0041521

The Ameliorative Effect of Cleome droserifolia (Samwa) on Myocardial Injury Associated with Diabetes in Male Rats

Article 8, Volume 69, Issue 4, October 2017, Page 2222-2231  XML PDF (407.55 K)
Document Type: Original Article
DOI: 10.12816/0041521
View on SCiNiTO View on SCiNiTO
Authors
El-Komy MM; Serag MH and Emsalam AA email
Faculty of Science, Mansoura University Egypt
Abstract
Background: Diabetes is an imperative risk factor for cardiac complications development. Cleome droserifolia (Cd) is used in Egyptian traditional medicine for treatment of diabetes mellitus. Aim: The aim of the present study was to measure the possible protective effects of ethanolic extract of Cd against cardiacmyopathy in Streptozotocin (STZ) induced diabetic rats. Materials and Methods: Experimental diabetes was induced by intrapritoneal injection with a single dose of STZ (45 mg/kgbw). Oral dose Cd extract was administered daily for four weeks (310 mg/kg bw). Results: Diabetic rats exhibited an increase in glucose level and lipid profile as well as cardiacpro-inflammatory, pro-apoptotic markers and oxidative stress, while a decrease was recorded in antioxidant enzymatic activities. On the other hand the administration of diabetic rats with Cdextract for four weeks resulted in a significant amelioration in the most of the parameters mentioned above when compared with diabetic rats. Conclusion: The data clearly indicated that the treatment with Cleome droserifolia exerts a therapeutic protective nature in cardiac complications due to diabetes by decreasing oxidative stress and cardiac damage which may be attributed to its antioxidative potential.
 
Keywords
diabetic rats; streptozotocin; Heart injury; Cleome droserifolia
Statistics
Article View: 189
PDF Download: 397