Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats

Helal, Eman; Sayed, Rasha A. A. El; Ebrahiem, Sara

doi:10.12816/0041072

Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats

Document Type : Original Article

Authors

Department of Zoology, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt.

10.12816/0041072

Abstract

Background: this study aimed to illustrate the protective effect of red cabbage extract against hyperthyroidism induced by L-thyroxin in male albino rats. Materials and methods: Eighteen animals were divided randomly into three groups. Group A: healthy rats, Group B: normal rats were subcutaneous injected with 500 µg/kg body weight/day L-thyroxin once daily for two weeks to induce hyperthyroidism and group C: hyperthyroid rats received red cabbage extract. At the end of the experiment, blood samples were collected for biochemical analysis. Results: hyperthyroid rats induced by L-thyroxin had significant decrease (P<0.05) in serum levels of triodothyronine (T3), thyroxin (T4), protein profile, lipid profile (TC, HDL) as well as a significant increase in kidney function test (BUN, uric acid), in liver enzymes (ALP, ALT), and a significant decrease in TSH, TG, VLDL compared to the normal control group. Oral administration of red cabbage extract ameliorated most of the tested parameters.

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