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Helal, E., Sayed, R., Ebrahiem, S. (2017). Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats. The Egyptian Journal of Hospital Medicine, 69(3), 2137-2142. doi: 10.12816/0041072
Eman Helal; Rasha A. A. El Sayed; Sara Ebrahiem. "Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats". The Egyptian Journal of Hospital Medicine, 69, 3, 2017, 2137-2142. doi: 10.12816/0041072
Helal, E., Sayed, R., Ebrahiem, S. (2017). 'Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats', The Egyptian Journal of Hospital Medicine, 69(3), pp. 2137-2142. doi: 10.12816/0041072
Helal, E., Sayed, R., Ebrahiem, S. Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats. The Egyptian Journal of Hospital Medicine, 2017; 69(3): 2137-2142. doi: 10.12816/0041072

Effect of Egyptian Red Cabbage on Some Physiological Parameters in Hyperthyroidimic Rats

Article 24, Volume 69, Issue 3, October 2017, Page 2137-2142  XML PDF (269.46 K)
Document Type: Original Article
DOI: 10.12816/0041072
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Authors
Eman Helal email orcid ; Rasha A. A. El Sayed; Sara Ebrahiem
Department of Zoology, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt.
Abstract
Background: this study aimed to illustrate the protective effect of red cabbage extract against hyperthyroidism induced by L-thyroxin in male albino rats. Materials and methods: Eighteen animals were divided randomly into three groups. Group A: healthy rats, Group B:   normal rats were subcutaneous  injected with 500 µg/kg body weight/day L-thyroxin once daily for two weeks to induce hyperthyroidism and group C: hyperthyroid rats received red cabbage extract. At the end of the experiment, blood samples were collected for biochemical analysis. Results: hyperthyroid rats induced by L-thyroxin had significant decrease (P<0.05) in serum levels of triodothyronine (T3), thyroxin (T4), protein profile, lipid profile (TC, HDL) as well as a significant increase in kidney function test (BUN, uric acid), in liver enzymes (ALP, ALT), and a significant decrease in TSH, TG, VLDL compared to the normal control group. Oral administration of red cabbage extract ameliorated most of the tested parameters.
Keywords
hyperthyroidism- red cabbage- rat- kidney function
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