Nassef, H., Sheha, A., Radhi, A. (2017). The Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation. The Egyptian Journal of Hospital Medicine, 69(2), 1908-1910. doi: 10.12816/0040621
Hana Hamdy Nassef; Aliaa Sayed Sheha; Ali Abbass Radhi. "The Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation". The Egyptian Journal of Hospital Medicine, 69, 2, 2017, 1908-1910. doi: 10.12816/0040621
Nassef, H., Sheha, A., Radhi, A. (2017). 'The Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation', The Egyptian Journal of Hospital Medicine, 69(2), pp. 1908-1910. doi: 10.12816/0040621
Nassef, H., Sheha, A., Radhi, A. The Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation. The Egyptian Journal of Hospital Medicine, 2017; 69(2): 1908-1910. doi: 10.12816/0040621
The Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation
Department of Radio-diagnosis, Faculty of Medicine, Ain Shams University
Abstract
Background: hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Surgical resection and local ablative therapies represent the most frequent first lines therapies adopted when liver transplantation cannot be offered. Aim of the work:this study aimedto evaluate the feasibility of DWI and the corresponding ADC values to detect tumor response after radiofrequency ablation for hepatocellular carcinoma. Patients and methods: MR examinations were done for 20 HCC patients post-RFA. Pre and post gadolinium enhanced images as well as DW sequences were performed. ADC values of ablation zones and liver parenchyma were assessed. ADC values of ablation zones and adjacent signal alterations identified in DWI were analyzed. Results:residual or recurrent lesions were detected in 4 patients (20%). The mean ADC value of ablated zones differed significantly from that of normal liver parenchyma. The corresponding ADC values were significantly lower in patients with residual lesion than in patients without residual lesion. Conclusion: it can be concluded that DWI is a feasible follow-up tool for post ablation liver contributing in detection of residual lesion.