Nonalcoholic Fatty Liver Disease (NAFLD)

Gashgari, Abrar Mohammed Noor; Alhusainy, Khalid Mohamad; Alharbi, Fahad Obaid Eid; Hani M, Al Qahtany Faisal; Omer, Abdulaziz Mohammed; Alali, Abdulaziz Hamad; Moharaq, Firas Ibrahim; Soufi, Ziad Marwan; Boundaqji, Khaled Rashad; Sayyal, Rayyan Ibrahim; Alsharif, Mohammed

doi:10.12816/0042982

Nonalcoholic Fatty Liver Disease (NAFLD)

Document Type : Original Article

Authors

¹ Baterjee Medical Collage

² Majmaah University

³ Qassim University

⁴ Imam Abdulrahman Bin Faisal University

⁵ Imam Mohammed Bin Saud University

⁶ Umm Al Qura University

⁷ Ibn Sina National College

⁸ Taif University

10.12816/0042982

Abstract

Background: Nonalcoholic fatty liver disease is the most frequent cause of liver diseaseacross the world. Its pathophysiology is considered multifaceted and is controlled by numerous mechanisms comprising environmental, metabolic, genetic, and gut microbial factors. Diagnosis of nonalcoholic fatty liver disease poses a challenge owing to its subtle and non-specific presentation.
Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE from January 1987 to March 2017. The following search terms were used: fatty liver disease, nonalcoholic liver disease, chronic liver disease, diagnosis and management of liver pathology
Aim of the work: In this study we aimed to understand about the pathophysiology, diagnosis, management and prognosis of nonalcoholic fatty liver disease.
Conclusion: More studies must be done to formulate a more definite and reliable diagnostic method. General practitioners and specialists must be informed of the possible manifestation sings to keep higher degree of suspicion. Once NAFLD is established, frequent follow-up and proper management can reduce complications and improve prognosis.

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