Insulin-Like Growth Factor Binding Protein-1 versus Cervical Length in Prediction of Successful Induction of Labor after 37 Week. Observational Study

Elnasr, Ibrahim Saif; Said, Dalia Sabry Mohamed; Omar, Thoria Ahmed; Ammar, Hesham

doi:10.21608/ejhm.2020.112314

Insulin-Like Growth Factor Binding Protein-1 versus Cervical Length in Prediction of Successful Induction of Labor after 37 Week. Observational Study

Document Type : Original Article

Authors

10.21608/ejhm.2020.112314

Abstract

Background: Bishop Score is still the usual method to expect the results of labor induction. Transvaginal ultrasonographic measurement of cervical length (TVUS-CL) is more objective and insulin like growth factor binding protein-1(IGFBP-1) has been recently used for this aim.
Objective: This study was conducted to compare between TVUS-CL and detection of cervical (IGFBP-1) for prediction of results of induction of labor after 37 week of pregnancy.
Patients and Methods: A prospective cohort study on 140 pregnant women underwent induction of labor. All patients were subjected to TVUS-CL and detection of cervical (IGFBP-1) and Bishop Score. The primary outcome measure was induction success. The secondary outcome measure was induction to delivery interval.
Results: In our study (97) females delivered by simple vaginal delivery (SVD), (79) females delivered within 24 hour of induction, (18) females delivered after 24 hour, and (43) females delivered by caesarian section. The mean cervical length measured by TVUS in females who delivered by SVD was 24.89 ±5.48 mm and was 26.79±3.06 mm in those who delivered by CS. IGFBP-1 was positive in 71 females who delivered by SVD and in 17 females who delivered by CS and it was negative in 26 females who delivered by SVD and 26 females who delivered by CS.
Conclusion: Success of labor induction correlated significantly with detection of cervical IGFBP-1 and measurement of cervical length by TVUS.

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