Background: Diabetes mellitus was defined by World health Organization as a metabolic disorder which characterized by chronic hyperglycemia. It is a disease with several etiologies. It is one of common diseases in children. School children with diabetes need special care while they are in school as they may experience problems in glucose levels or other problems. Teachers are persons responsible for children in school, so they should have adequate information and good level of awareness about diabetes to deal with diabetic children especially in emergency case. Aim: To assess the awareness of school teachers about diabetes. Methods: This cross-sectional study was performed in the period between October 2017 and November 2017 on school teachers in Makah region using a questionnaire. Data were analyzed by SPSS program. Results: There were 58.4% males and 41.6% females in this study, the correlations between level of knowledge and different variables were as follow; the age of teachers significantly (P-value=0.009) affected the level of awareness, where teachers with older age (≥50 years) had the highest awareness among other participants, while those with age 40-49 years were the dominant group to have both moderate 30 (58.8%) and low awareness 20 (39.2%). Gender also was a significant factor that affected the level of awareness (P-value=0.004), where males 23 (33.8) had high level of awareness than females 3 (12.6%). Conclusion: There was moderate level of knowledge about diabetes among school teachers. Age, gender, level of education and monthly income affected the level of knowledge.