Helal, E., Khattab, H., Aggad, W., Okasha, H. (2023). Effect of Flaxseed or Turmeric Oils on Reproductive Parameters and Serum Oxidative Stress Markers of Male Albino Rats (Rattus Rattus). The Egyptian Journal of Hospital Medicine, 92(1), 5608-5614. doi: 10.21608/ejhm.2023.306173
Eman Helal; Hala A.H. Khattab; Waheeb S. Aggad; Hager S. Okasha. "Effect of Flaxseed or Turmeric Oils on Reproductive Parameters and Serum Oxidative Stress Markers of Male Albino Rats (Rattus Rattus)". The Egyptian Journal of Hospital Medicine, 92, 1, 2023, 5608-5614. doi: 10.21608/ejhm.2023.306173
Helal, E., Khattab, H., Aggad, W., Okasha, H. (2023). 'Effect of Flaxseed or Turmeric Oils on Reproductive Parameters and Serum Oxidative Stress Markers of Male Albino Rats (Rattus Rattus)', The Egyptian Journal of Hospital Medicine, 92(1), pp. 5608-5614. doi: 10.21608/ejhm.2023.306173
Helal, E., Khattab, H., Aggad, W., Okasha, H. Effect of Flaxseed or Turmeric Oils on Reproductive Parameters and Serum Oxidative Stress Markers of Male Albino Rats (Rattus Rattus). The Egyptian Journal of Hospital Medicine, 2023; 92(1): 5608-5614. doi: 10.21608/ejhm.2023.306173
Effect of Flaxseed or Turmeric Oils on Reproductive Parameters and Serum Oxidative Stress Markers of Male Albino Rats (Rattus Rattus)
Background: Phytoestrogens are estrogen analogues of plant origin, allowing them to act as agonists at estrogen receptors. Objectives: This study was done to discover the effects of flaxseed and turmeric oils on male rats' fertility. Methodology: Eighteen male albino rats are divided into three groups (6 rats each). Group 1 ( Control group) rats received distilled water 1 mL/kg orally); group 2 (Flaxseed oil group) rats received 1 mL/kg flaxseed oil orally;group 3 (Turmeric oil) rats received 1 mL/kg turmeric oil orally. After 30 days, blood samples, epididymis, and testis were collected for biochemical analysis, sperm characteristics and histological examinations. Results: Flaxseed oil induced a significant decline (p < 0.05) in % of body weight change relative to the control group. Flaxseed and turmeric oils groups showed significant declines (p < 0.05) in gonadosomatic index and sperm motility, concentration, and viability, with a significant increase in sperm abnormalities. Besides, Flaxseed and turmeric oils groups showed significant decreases (p < 0.05) in the serum testosterone levels with significant increases (p < 0.05) in serum prolactin, FSH, and LH levels. Flaxseed and turmeric oils consumption significantly decreased (p < 0.05) plasma CAT and SODwhile they significantly increased (p < 0.05) plasma MDA relative to the control group. The testis of rats ingested flaxseed and turmeric oils showed degenerated seminiferous tubules, with a diminished number of mature spermatozoa in the tubular lumen, reduced diameter of seminiferous tubules and intact basement membrane. Conclusion: Feeding flaxseed and turmeric oils consumption to adult male rats induced hormonal disturbances with non-uniformities in sperm characteristics.