bedier, A., Rizq, A., Shehab Eldin, M., Teima, S. (2023). Left Ventricular Longitudinal Strain Following Revascularization in Acute ST Segment Elevation Myocardial Infarction: A Comparison of Primary Angioplasty and Streptokinase Based Pharmacoinvasive Strategy. The Egyptian Journal of Hospital Medicine, 90(1), 1537-1541. doi: 10.21608/ejhm.2023.282504
ahmed bedier; Ahmed Elsayed Rizq; Mohamed Bayoumi Shehab Eldin; Sally Magdy Teima. "Left Ventricular Longitudinal Strain Following Revascularization in Acute ST Segment Elevation Myocardial Infarction: A Comparison of Primary Angioplasty and Streptokinase Based Pharmacoinvasive Strategy". The Egyptian Journal of Hospital Medicine, 90, 1, 2023, 1537-1541. doi: 10.21608/ejhm.2023.282504
bedier, A., Rizq, A., Shehab Eldin, M., Teima, S. (2023). 'Left Ventricular Longitudinal Strain Following Revascularization in Acute ST Segment Elevation Myocardial Infarction: A Comparison of Primary Angioplasty and Streptokinase Based Pharmacoinvasive Strategy', The Egyptian Journal of Hospital Medicine, 90(1), pp. 1537-1541. doi: 10.21608/ejhm.2023.282504
bedier, A., Rizq, A., Shehab Eldin, M., Teima, S. Left Ventricular Longitudinal Strain Following Revascularization in Acute ST Segment Elevation Myocardial Infarction: A Comparison of Primary Angioplasty and Streptokinase Based Pharmacoinvasive Strategy. The Egyptian Journal of Hospital Medicine, 2023; 90(1): 1537-1541. doi: 10.21608/ejhm.2023.282504
Left Ventricular Longitudinal Strain Following Revascularization in Acute ST Segment Elevation Myocardial Infarction: A Comparison of Primary Angioplasty and Streptokinase Based Pharmacoinvasive Strategy
department of cardiology , mansoura university , Egypt
Abstract
Background: Two-dimensional speckle-tracking echocardiography (2D STE) has been proven to be more accurate than prognostic metrics such as the left ventricular ejection fraction (LVEF) and wall motion score index (WMSI). Aim: To contrast the effectiveness of primary percutaneous coronary intervention (PCI) versus Streptokinase based pharmacoinvasive technique in ST elevation myocardial infarction (STEMI) patients. Patients and methods: In this observational cross section research, 100 patients with acute STEMI were enrolled. They were then divided into two groups: Group A, which included 50 patients who underwent primary PCI as a reperfusion strategy, and Group B, which included 50 patients who underwent pharmacoinvasive technique, which involved streptokinase IV infusion, over the course of a year from November 2020 to November 2021. In order to evaluate the main outcome, which was LV systolic function, all patients had a thorough medical history review, physical examination, 12-lead surface ECG, and echocardiogram (2D global longitudinal strain [GLS] utilizing speckle tracking echocardiography [STE]. Results: Pre-intervention GLS showed no statistically substantial variation between the two groups (p=0.768), however post-treatment GLS showed statistically substantial variations between the two groups (p=0.004) and regarding change (%) GLS (p˂ 0.001). Conclusion: Primary PCI remains the best option for resolving ischemia. When compared to IV streptokinase treatment, direct coronary angioplasty exhibited a substantial clinical advantage. To treat the myocardial infarction, it was superior to streptokinase based pharmacoinvasive therapy.