Elrefai, L., Allam, M., El-zahi, M., Akl, F. (2022). Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer. The Egyptian Journal of Hospital Medicine, 89(2), 7082-7090. doi: 10.21608/ejhm.2022.273046
Lamiaa Ahmed Elrefai; Magda Elsayed Hassan Allam; Mohamed Saad El-deen El-zahi; Fatma Mohamed Farouk Akl. "Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer". The Egyptian Journal of Hospital Medicine, 89, 2, 2022, 7082-7090. doi: 10.21608/ejhm.2022.273046
Elrefai, L., Allam, M., El-zahi, M., Akl, F. (2022). 'Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer', The Egyptian Journal of Hospital Medicine, 89(2), pp. 7082-7090. doi: 10.21608/ejhm.2022.273046
Elrefai, L., Allam, M., El-zahi, M., Akl, F. Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer. The Egyptian Journal of Hospital Medicine, 2022; 89(2): 7082-7090. doi: 10.21608/ejhm.2022.273046
Impact of Ablative Low Dose Radio-Active Iodine after Thyroidectomy in Low–Risk Differentiated Thyroid Cancer
Clinical Oncology& Nuclear Medicine Department, Faculty Of Medicine, Mansoura University.
Abstract
Background:Thyroid cancer (TC) is the most frequent endocrine cancer, comprising for 3-4% of all tumors. Objective: The aim of the current study was to assess the efficacy, safety, and disease-free survival of low-dose RAI (iodine-131) in patients with low-risk differentiated thyroid cancer (DTC) who had low-dose RAI for thyroid residual ablation after full or near-total thyroidectomy. Patients and methods: Between January 2013 and July 2019, 35 patients with low-risk well-differentiated thyroid cancer were investigated by the Clinical Oncology and Nuclear Department at Mansoura University Hospitals. Results: The majority of our patients (94.3%) were females. A total of 34 (97.1%) patients had papillary thyroid cancer and 1 (2.8 %) patient had follicular thyroid carcinoma. All patients were Stage I; 13 (37.1%) patients were T1, and 22 (62.9%) patients were T2 thyroid carcinoma. All patients had pathologically negative lymph nodes and 8 (22.8%) patients had complete thyroidectomy with block neck dissection (BND), whereas the remaining 27 (77.1%) patients had total thyroidectomy without BND. Conclusion: Low-dose radioactive iodine ablation following surgery is an effective approach for treating low-risk DTC, because it decreases the side effects while preserving a good quality of life.