.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. (2018). Evaluation of Some Biochemical Changes in Diabetic Patients. The Egyptian Journal of Hospital Medicine, 50(1), 150-155. doi: 10.21608/ejhm.2018.16084
M.A .El-desoky; A.E. Amin; M.O .El-refai; R.J. Farid; A.A. Labib. "Evaluation of Some Biochemical Changes in Diabetic Patients". The Egyptian Journal of Hospital Medicine, 50, 1, 2018, 150-155. doi: 10.21608/ejhm.2018.16084
.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. (2018). 'Evaluation of Some Biochemical Changes in Diabetic Patients', The Egyptian Journal of Hospital Medicine, 50(1), pp. 150-155. doi: 10.21608/ejhm.2018.16084
.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. Evaluation of Some Biochemical Changes in Diabetic Patients. The Egyptian Journal of Hospital Medicine, 2018; 50(1): 150-155. doi: 10.21608/ejhm.2018.16084
Evaluation of Some Biochemical Changes in Diabetic Patients
1Department of Chemistry,Biochemistry Division, Faculty of Science, Cairo University.
2Department of Clinical Pathology, Faculty of Medicine, Cairo University
3M.Sc candidate, Faculty of Science, Cairo University
Abstract
Patients and methods: The present study consisted of 50 subjects were classified into three groups ; Group (GI) Control group consisted of 10 clinically healthy adult subjects of both sexes free from any liver , kidney or cardiovascular diseases . Group (GII) diabetes mellitus type 1 consisted of 20 patients of both sexes. Group (GIII) diabetes mellitus type 1 with nephropathy consisted of 20 patients of both sexes . All subjects were undergo to the following investigated parameters; Ascorbic acid (vitamin C) ,Catalase ,Total antioxidant capacity, Aldolase and Pyruvate kinase enzyme. Results: vitamins C, catalase, total antioxidant capacity enzymes were highly significant decreased (P < 0. 01) in diabetes mellitus type 1 (GII) and diabetes mellitus type 1 with nephropathy (GIII) when compared to the control group. Adolase activity washighly significant increased (P < 0. 01) in diabetes mellitus type 1 with nephropathy (GIII) when compared to the control group . Pyruvate Kinase activitywashighly significant increased (P < 0. 01) in diabetes mellitus type 1 (GII) when compared to the control group . Conclusion: The antioxidant and enzymes can be used for follow up in patients suffering from diabetes mellitus type 1 and predict other complications.