Hafez, M., Abdallah, H., Abdellatif, K. (2020). Prevalence of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites and Its Pattern in Aswan University Hospital. The Egyptian Journal of Hospital Medicine, 81(2), 1444-1448. doi: 10.21608/ejhm.2020.114452
Mohammed Zain-Eldeen Hafez; Hala Abdallah Mahmoud Abdallah; Khalid Khairy Khalafalla Abdellatif. "Prevalence of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites and Its Pattern in Aswan University Hospital". The Egyptian Journal of Hospital Medicine, 81, 2, 2020, 1444-1448. doi: 10.21608/ejhm.2020.114452
Hafez, M., Abdallah, H., Abdellatif, K. (2020). 'Prevalence of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites and Its Pattern in Aswan University Hospital', The Egyptian Journal of Hospital Medicine, 81(2), pp. 1444-1448. doi: 10.21608/ejhm.2020.114452
Hafez, M., Abdallah, H., Abdellatif, K. Prevalence of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites and Its Pattern in Aswan University Hospital. The Egyptian Journal of Hospital Medicine, 2020; 81(2): 1444-1448. doi: 10.21608/ejhm.2020.114452
Prevalence of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites and Its Pattern in Aswan University Hospital
1Department of Internal Medicine, Faculty of Medicine, Assiut University
2Department of Internal Medicine, Faculty of Medicine, Aswan University
Abstract
Background: Spontaneous bacterial peritonitis (SBP) is the most common infection and a lethal complication in patients with liver cirrhosis and ascites. It has high mortality and recurrence rates and poor long-term prognosis. Objective: This study was done to determine the prevalence of spontaneous bacterial peritonitis and its variants in patients of liver cirrhosis with ascites. Patients and Methods: This was a prospective, randomized, cross-sectional clinical study, included 100 adult patients of decompensated liver cirrhosis with ascites in Aswan University Hospital during the period from January 2019 to December 2019. Results: Diagnosis of SBP is based on ascitic fluid analysis as well as culture and sensitivity. The diagnostic criteria are PMNL > 250/mm³ and or positive culture. Mean of age of patients was 63.06 ± 9.67 years old. Majority of patients were males (63%) and 37 % were females. In Our study, 62% of patients were diagnosed SBP. Classic SBP in 30.6%, Culture Negative Neutrocytic Ascites (CNNA) in 59.7% and MNB in 9.7% of patients. Of 25 patients who have positive culture ascetic fluid, 60% were positive for gram-negative bacteria predominantly E. coli. Conclusion: Spontaneous Bacteria Peritonitis is the most common and life-threatening infection in patients who have liver cirrhosis and ascites. It is diagnosed by a) Ascitic fluid PMNL > 250/mm³. b) Positive ascetic fluid culture. c) Both a and b. It is found that SBP has recently increased in prevalence with predominantly causative organism gram negative E Coli.