Hairy cell leukemia is a rare disease comprising about 2% of lymphoid neoplasms. In this review, the biology, diagnostic criteria, and current therapeutic options in HCL-V and HCL-JV are presented.We conducted a database; PubMed and Embase comprehensive search up to December 2017, we search a relevant trail to our concern topic (hairy cell leukemia). HCL-V is a distinct clinico-pathological entity. However, differentiating HCL-V from classical HCL and splenic marginal zone lymphoma (SMZL), which are both connected with noticeable splenomegaly and circulating neoplastic cells with 'hairy' projections remain a problem. Patients with HCL-V are usually older, splenomegaly is less typical and leucopenia with granulocytopenia and monocytopenia are generally not seen. Bone marrow is usually easily aspirable, hyper-cellular with mild myelofibrosis.
Halah Ahmad Alfaraj, Ranim Yahya Nasr, A. A. A. B. S. A. H. A. A. (2018). Management Approaches to Hairy Cell Leukemia; Overview. The Egyptian Journal of Hospital Medicine, 71(1), 2257-2261.
MLA
Akeelah Abdullah Al-Haddad, Batool Saad Alsalim, Huriyyah Alawi AlJarrash, Halah Ahmad Alfaraj, Ranim Yahya Nasr. "Management Approaches to Hairy Cell Leukemia; Overview", The Egyptian Journal of Hospital Medicine, 71, 1, 2018, 2257-2261.
HARVARD
Halah Ahmad Alfaraj, Ranim Yahya Nasr, A. A. A. B. S. A. H. A. A. (2018). 'Management Approaches to Hairy Cell Leukemia; Overview', The Egyptian Journal of Hospital Medicine, 71(1), pp. 2257-2261.
VANCOUVER
Halah Ahmad Alfaraj, Ranim Yahya Nasr, A. A. A. B. S. A. H. A. A. Management Approaches to Hairy Cell Leukemia; Overview. The Egyptian Journal of Hospital Medicine, 2018; 71(1): 2257-2261.