Matrix Metalloproteinase 7 in Rheumatoid Arthritis Patients with Interstitial Lung Disease

Document Type : Original Article

Author

Faculty of Medicine–Ain Shams University

Abstract

The study aim: The purpose of this study is to measure the matrix metalloproteinase 7 (MMP7) in rheumatoid arthritis (RA) patients with interstitial lung disease (ILD) and to assess for any correlation with RA-disease activity. Research design: A cross sectional study. Sample: a purposive sample included 40 rheumatoid arthritis patients from Ain Shams University Hospitals Inpatient Department of Rheumatology and Outpatient Clinic. The results revealed that serum (S) MMP7 was significantly higher among RA patients with interstitial lung disease than patients without. Conclusion: The study documented that S.MMP7 may be used as a screening test for detection of interstitial lung disease in patients with rheumatoid arthritis. The study recommended: Measurement of serum MMP7 level to RA patients may be used as screening test for detection of ILD

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