Background: Breast cancer is the most common type of cancer found in women and today represents a significant challenge to public health. Postoperative pain is the most distressing symptom experienced by the patient. Pain induces metabolic, hormonal and cardio-respiratory responses that affect the outcome of surgery. Aim of the Work: The aim of this study was to evaluate the role of ketamine as an adjuvant to bupivacaine in c- arm guided thoracic paravertebral block analgesia for modified radical mastectomy. Patients and Methods: This study was carried out in Tanta University Hospitals in Surgery Department from April 2016 to October 2016 on sixty-two patients scheduled for elective modified radical mastectomy divided into two equal groups each contain 31 patients, group 1 received PVB with bupivacaine only under c arm and group 2 received PVB with bupivacaine and ketamine as pre emptive analgesia and watch what is the outcome. Written informed consent was taken from each patient. Results: This prospective randomized double blind study was carried out on 62 patients divided into two equal groups where group two showed statistically significant decrease in VAS , total amount of analgesic and delay in time of first analgesic requirement in comparison with group one and significant difference as regard hemodynamics and postoperative complication between two groups. Conclusion: We concluded that addition of ketamine to bupivacaine as an adjuvant in C-arm guided PVB appears to be more beneficial than the use of bupivacaine alone for postoperative analgesia in modified radical mastectomy surgery.
Areeg Kotb Ghalwash 2, S. M. E. 1. N. A. E. S. 1. A. F. A. 1. (2018). Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy. The Egyptian Journal of Hospital Medicine, 71(5), 3153-3157.
MLA
Sanaa Mohamed Elnoamany 1, Nabil Ali El Sheikh 1, Asmaa Fawzy Amer 1, Areeg Kotb Ghalwash 2. "Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy", The Egyptian Journal of Hospital Medicine, 71, 5, 2018, 3153-3157.
HARVARD
Areeg Kotb Ghalwash 2, S. M. E. 1. N. A. E. S. 1. A. F. A. 1. (2018). 'Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy', The Egyptian Journal of Hospital Medicine, 71(5), pp. 3153-3157.
VANCOUVER
Areeg Kotb Ghalwash 2, S. M. E. 1. N. A. E. S. 1. A. F. A. 1. Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy. The Egyptian Journal of Hospital Medicine, 2018; 71(5): 3153-3157.
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