Effect of Weight Bearing Exercises on Osteoporosis in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

El Azizy, Amr El Sayed; Ahmed, Emad Tawfik; Abd Elbary, Naser; Mogahed, Hussein Gamal Hussein

doi:10.21608/ejhm.2020.72544

Effect of Weight Bearing Exercises on Osteoporosis in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

Document Type : Original Article

Authors

¹ Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt

² Clinical Oncology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

10.21608/ejhm.2020.72544

Abstract

Background: Most men diagnosed with prostate cancer (PCa) are aged 50 years old or more treated by androgen deprivation therapy (ADT) treatment has been associated with interconnected adverse effects as decreased bone mineral density (BMD) and a loss in the structure and strength of bone leading to osteoporosis. Exercise has been proposed as a treatment to mitigate side effects of ADT. Objective: This study was conducted to evaluate the effect of weight bearing exercises on osteoporosis in prostate cancer patients undergoing androgen deprivation therapy. Patients and methods: The current study was conducted during a period of 3 months starting from 1st October 2019 till 31st December 2019.Thirty PCa patients who had osteoporosis induced by ADT were participated in this study, their ages were over 50 years old. They were selected from the Oncology Hospital Menoufia University and randomly distributed into two equal groups, group A: included 15 patients who received 30 minutes of weight bearing exercises through walking on treadmill, in addition to conventional medical care 3 days /week and group B: included 15 patients who on their conventional medical care. Results: Our study showed that there was a statistically significant improvement in BMD and T-score mean of spine, femoral neck and total femur post treatment compared to that pre-treatment in the group A and B. Conclusion: It can be concluded that weight bearing exercises had fruitful effects in cases of osteoporosis in prostate cancer patients undergoing androgen deprivation therapy as evidenced by the significant increase in BMD and T-score mean.

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