Tawakol, M., Tag El-Din, A., Hassan, A. (2019). Corneal Hysteresis before and after Corneal Collagen Cross Linking for Keratoconus. The Egyptian Journal of Hospital Medicine, 77(5), 5759-5765. doi: 10.21608/ejhm.2019.63232
Magdy Ezz-Eldin Tawakol; Abd El-Magid M. Tag El-Din; Amr Gamal Hassan. "Corneal Hysteresis before and after Corneal Collagen Cross Linking for Keratoconus". The Egyptian Journal of Hospital Medicine, 77, 5, 2019, 5759-5765. doi: 10.21608/ejhm.2019.63232
Tawakol, M., Tag El-Din, A., Hassan, A. (2019). 'Corneal Hysteresis before and after Corneal Collagen Cross Linking for Keratoconus', The Egyptian Journal of Hospital Medicine, 77(5), pp. 5759-5765. doi: 10.21608/ejhm.2019.63232
Tawakol, M., Tag El-Din, A., Hassan, A. Corneal Hysteresis before and after Corneal Collagen Cross Linking for Keratoconus. The Egyptian Journal of Hospital Medicine, 2019; 77(5): 5759-5765. doi: 10.21608/ejhm.2019.63232
Corneal Hysteresis before and after Corneal Collagen Cross Linking for Keratoconus
Department of Ophthalmology - Faculty of Medicine, Al Azhar University
Abstract
Background: Corneal collagen cross-linking (CXL) has been used as a treatment option in patients with either keratoconus or iatrogenic corneal ectasia after LASIK. The purpose of corneal cross-linking is to stabilize the corneal stroma and to delay the progression of these two pathologic entities. Objective: The aim of this study is to compare the corneal hysteresis before and after corneal collagen cross-linking using riboflavin and ultraviolet-A light by the epithelial-off technique for treatment of keratoconus. Patients and methods: This study is a single-centre prospective interventional study. It was conducted between April 2018 to December 2018 and included 30 eyes of 18 patients with a mean age 27.08 years (range from 17- 30). They were 12 female eyes and 18 male eyes; all underwent corneal collagen cross-linking using riboflavin and ultraviolet-A light at Kobry El Kobba Military Specialized Eye Hospital. Results: All patients were evaluated preoperatively for their uncorrected corrected visual acuity (UCVA), best corrected visual acuity (BCVA), k-reading, spherical equivalent and pachymetry (using Pentacam), and corneal biomechanical properties (using ocular response analyzer (ORA). The mean age was 27.08±7.86 years, and postoperative follow up was at 1 and 4 months. The mean CH was 7.93±1.79 mmHg preoperatively, 8.27±1.22 mmHg at 1 month, 8.99±1.24 mmHg at 4 months, which show a statistically significant increase in the mean CH pre- and postoperatively, while CRF the other parameter, show a highly statistically significant decrease pre- and postoperatively. Conclusion: CXL is a promising new treatment modality for keratoconus patients and may affect corneal biomechanics.
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