Role of Cardiac MR Imaging in Evaluation of Left Ventricular Diastolic Function in Ischemic Heart Disease

Document Type : Original Article

Authors

Department of Diagnostic Radiology, Faculty of Medicine, Al-Azhar University

Abstract

Background: Diastolic dysfunction and coronary artery disease (CAD) are interrelated. The complications of CAD, myocardial ischemia or infarction, are major causes of diastolic dysfunction. Objective: The aim of this study was to determine the accuracy of CMR in assessment of left ventricular diastolic function in ischemic heart disease patients by using a combination of left atrium size measurement and phase-contrast evaluation of transmitral flow. Also, to evaluate the extent of myocardial scarring in these patients and to correlate between the degree of myocardial scarring and the degree of left ventricular diastolic dysfunction. Patients and methods: In the current study a total number of 22 patients with known ischemic heart disease were enrolled for contrast enhanced CMR examination between January 2019 and October 2019. All patients underwent CMR and echocardiography. Two of the 22 patients were excluded from the study because of technical difficulties or failure of data acquisition (patient did not hear or did not obey breathing instructions). So, 20 patients were included in the present study. Results: our study showed feasibility of routinely performing evaluation of MV flow to assess diastolic function using CMR. We were able to obtain clinical variables including E:A ratios and deceleration times, which agreed with those obtained using TTE. Conclusion: In patients with CAD, extent of myocardial scarring reliably predicts the degree of diastolic dysfunction. LGE-CMR provides a powerful means to noninvasively assess the degree of myocardial scarring.

Keywords

The Egyptian Journal of Hospital Medicine
Volume 77, Issue 4
October 2019
Pages 5507-5513

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