Nooreldin, A., Abdelkareem, M., Ibrahim, A., Mahmoud, A. (2019). Ultrasonographic Enthesis Evaluation in Patients with Recurrent Acute Anterior Uveitis with and without Spondyloarthropathy. The Egyptian Journal of Hospital Medicine, 76(7), 4608-4615. doi: 10.21608/ejhm.2019.45648
Asaad Nooreldin; Mohamed Ismail Abdelkareem; Ahmed Moslam Ibrahim; Amr Mohamed Mahmoud. "Ultrasonographic Enthesis Evaluation in Patients with Recurrent Acute Anterior Uveitis with and without Spondyloarthropathy". The Egyptian Journal of Hospital Medicine, 76, 7, 2019, 4608-4615. doi: 10.21608/ejhm.2019.45648
Nooreldin, A., Abdelkareem, M., Ibrahim, A., Mahmoud, A. (2019). 'Ultrasonographic Enthesis Evaluation in Patients with Recurrent Acute Anterior Uveitis with and without Spondyloarthropathy', The Egyptian Journal of Hospital Medicine, 76(7), pp. 4608-4615. doi: 10.21608/ejhm.2019.45648
Nooreldin, A., Abdelkareem, M., Ibrahim, A., Mahmoud, A. Ultrasonographic Enthesis Evaluation in Patients with Recurrent Acute Anterior Uveitis with and without Spondyloarthropathy. The Egyptian Journal of Hospital Medicine, 2019; 76(7): 4608-4615. doi: 10.21608/ejhm.2019.45648
Ultrasonographic Enthesis Evaluation in Patients with Recurrent Acute Anterior Uveitis with and without Spondyloarthropathy
1Departments of Ophthalmology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt
2Departments of Rheumatology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt
Abstract
Background: spondyloarthritis (SpA) is a group of chronic diseases recognized by arthritis and extraarticular lesions e.g. uveitis, enthesitis, dermatological affection. About 35% of SpA patients may present with recurrent attacks of acute anterior uveitis (AAU). Purpose: it was to detect whether patients with idiopathic recurrent AAU who were positive or negative for Human Leukocyte Antigen B27 (HLA–B27) had a frequency of enthesis lesions compared to that seen in patients with SpA. Patients and Methods: a prospective study of enthesis evident on musculoskeletal ultrasound examination was done on sixty patients and twenty controls, the eighty were categorized into 4 groups; group 1 included 20 patients with known SpA group 2 included 20 with recurrent AAU HLA–B27 positive and didn’t have SpA aspects group 3 included 20 with recurrent AAU HLA–B27 negative and didn’t have SpA and group 4 included 20 healthy controls. Using Madrid Sonography Enthesitis Index (MASEI) twelve enthesis locations were assessed in each participant. Results: a total of 960 entheses sites were examined by ultrasonography in all 80 participants. The MASEI cut-off limit of ≥18 points was 75%, 60%, 45%, and 10% of the participants in the 4 groups; respectively. The MASEI score was significantly higher in groups 1&2 than in groups 3&4. The differences between the two groups were statistically significant. Conclusion: a high percent of HLA–B27 positive patients with idiopathic recurrent AAU without characteristics of SpA have enthesis lesions with about percent to those seen in patients with known SpA.
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