Impacts of Chronic Obstructive Pulmonary Disease on Left Atrial and Left Ventricular dysfunction in Patients with Acute Myocardial Infarction: Strain Analysis Using Speckle-Tracking Echocardiography

doi:10.21608/ejhm.2025.451209

Impacts of Chronic Obstructive Pulmonary Disease on Left Atrial and Left Ventricular dysfunction in Patients with Acute Myocardial Infarction: Strain Analysis Using Speckle-Tracking Echocardiography

Document Type : Original Article

10.21608/ejhm.2025.451209

Abstract

Background: Despite the initial assumption that chronic obstructive pulmonary disease (COPD) solely distresses the lungs and airways, the focus of research has lifted to the great incidence of cardiovascular disease in COPD patients. This study aim was toassess the impacts of COPD on left atrial and left ventricular dysfunction in patients with acute myocardial infarction (AMI) using speckle-tracking echocardiography.

Patients and Methods: This reconsidering study was executed on eighty patients admitted with AMI. Patients were further subdivided into 2 sets: COPD group (40 patients) and non-COPD group (40 patients) regarding the GOLDEN criteria. Strain analysis by arterial blood gases (ABG), speckle-tracking echocardiography, pulmonary function tests (PFTs), and laboratory investigations were undertaken for all patients.

Results: Left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (LVGLS), left atrial strain during conduit stage (LAScd), left atrial strain during reservoir phase (LASr), and left atrial strain during contraction phase (LASct) were significantly increased in non-COPD patients than COPD patients (P value <0.001). LA volume and LAVI were significantly increased in COPD patients than non-COPD patients (P value <0.05). Left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD) were insignificantly changed among non-COPD and COPD patients.

Conclusions: left atrial and left ventricular diastolic dysfunction are prevalent in COPD patients following an AMI, as indicated by LA strain and LVGLS analyses. Additionally, it is imperative that cardiologists and pulmonologists collaborate more closely to improve the management of this substantial patient population.

Keywords