(2025). Clinical Manifestations of Patients with COVID Admitted to Tertiary Hospital. The Egyptian Journal of Hospital Medicine, 100(1), 3492-3497. doi: 10.21608/ejhm.2025.445982
. "Clinical Manifestations of Patients with COVID Admitted to Tertiary Hospital". The Egyptian Journal of Hospital Medicine, 100, 1, 2025, 3492-3497. doi: 10.21608/ejhm.2025.445982
(2025). 'Clinical Manifestations of Patients with COVID Admitted to Tertiary Hospital', The Egyptian Journal of Hospital Medicine, 100(1), pp. 3492-3497. doi: 10.21608/ejhm.2025.445982
Clinical Manifestations of Patients with COVID Admitted to Tertiary Hospital. The Egyptian Journal of Hospital Medicine, 2025; 100(1): 3492-3497. doi: 10.21608/ejhm.2025.445982
Clinical Manifestations of Patients with COVID Admitted to Tertiary Hospital
Background: Although COVID-19 has affected a substantial number of pediatric patients, severe illness remains relatively uncommon, with most children responding well to supportive care. The clinical presentation in this population is heterogeneous and frequently involves non-respiratory symptoms. However, adolescents and children with underlying medical comorbidities are more susceptible to developing significant respiratory complications. Objective: This study aimed to investigate the diversity of clinical presentations and imaging findings of COVID-19 among adolescents and children. Patients and methods: This observational, cross-sectional investigation was carried out between November 2022 and November 2023 at Mansoura University Children’s Hospital, Mansoura, Egypt. All enrolled patients underwent a comprehensive evaluation conducted more than four weeks after their initial COVID-19 diagnosis. The assessment included a structured interview by a senior pediatrician to evaluate the presence of ongoing symptoms and their impact on daily functioning. Radiological investigations comprised echocardiography, chest CT, EEG, and brain MRI. Results: Multisystem inflammatory syndrome in children (MIS-C) was identified in 22.2% of cases and represented the most frequent presentation of post-COVID syndrome. Other most reported symptoms included increased anxiety and worry (82.9%), fatigue (74.3%), breathlessness (68.6%), and the need to seek medical attention due to symptoms (60.0%). Other frequently reported symptoms were loss of appetite (57.1%), new-onset cough distinct from any pre-COVID cough (51.4%), and chest pain with palpitations (51.4%). Additional complaints included weak physical strength (37.1%), abdominal pain (34.3%), anosmia and headache (28.6%), altered sense of taste (25.7%), joint pain (22.9%), dizziness (17.1%), and diarrhea (11.4%). Notably, 11.4% of children reported that their symptoms had a negative impact on their school performance. Conclusion: A significant proportion of children experienced long-term physical and neuropsychiatric sequelae following COVID-19, with radiological evidence of persistent organ involvement observed in some cases. These findings underscore the need for structured follow-up and multidisciplinary care for pediatric COVID-19 survivors.
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