(2025). Comparative Study between Intrathecal (Dexmedetomidine versus Fentanyl) in Laparoscopic Cholecystectomies under Spinal Anesthesia. The Egyptian Journal of Hospital Medicine, 100(1), 3053-3059. doi: 10.21608/ejhm.2025.442175
. "Comparative Study between Intrathecal (Dexmedetomidine versus Fentanyl) in Laparoscopic Cholecystectomies under Spinal Anesthesia". The Egyptian Journal of Hospital Medicine, 100, 1, 2025, 3053-3059. doi: 10.21608/ejhm.2025.442175
(2025). 'Comparative Study between Intrathecal (Dexmedetomidine versus Fentanyl) in Laparoscopic Cholecystectomies under Spinal Anesthesia', The Egyptian Journal of Hospital Medicine, 100(1), pp. 3053-3059. doi: 10.21608/ejhm.2025.442175
Comparative Study between Intrathecal (Dexmedetomidine versus Fentanyl) in Laparoscopic Cholecystectomies under Spinal Anesthesia. The Egyptian Journal of Hospital Medicine, 2025; 100(1): 3053-3059. doi: 10.21608/ejhm.2025.442175
Comparative Study between Intrathecal (Dexmedetomidine versus Fentanyl) in Laparoscopic Cholecystectomies under Spinal Anesthesia
Background: General anesthesia was once believed to be the exclusive option for laparoscopy. However, regional anesthesia, including combination spinal epidural, spinal anesthesia, and epidural anesthesia, has advantages over general anesthetic these days.
Objective: An analysis of the clinical intraoperative results of intrathecal fentanyl and intrathecal dexmedetomidine in treating shoulder tip pain (STP) in patients undergoing laparoscopic cholecystectomy.
Patients and Methods: Patients undergoing cholecystectomy were randomly assigned into two equal groups based on a predefined randomization protocol. Group (D) was administered spinal anesthesia (SA) consisting of 3.0 ml levobupivacaine combined with 5 µg dexmedetomidine, making a total volume of 3.5 ml. Meanwhile, Group (F) received an intrathecal injection of 10 µg fentanyl (0.5 ml) along with 3.0 ml of 0.5% hyperbaric levobupivacaine.
Results: Spinal anesthetic combined with either fentanyl or dexmedetomidine was a viable option for treating shoulder tip discomfort in individuals undergoing laparoscopic cholecystectomy; the dexmedetomidine group experienced more improvement. Regarding hemodynamics, shoulder discomfort, and time to rescue analgesia, there were notable variations between the two groups. Conclusion: The two groups' rates of pneumoperitoneum, postoperative complications, muscle relaxation quality, and operational space adequacy were comparable.
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