Outcome And Short Term Follow Up of Transcatheter Perimembranous VSD Closure with Konar- Multifunctional Occluder Device in Children: A Tertiary Single Center Experience

Background: Transcatheter device closure of VSD has gradually become promising, especially for perimembranous defects with reported success rate of closure especially in pediatric population.
Objective: The study aimed to investigate the efficacy and the short-term outcome of using the innovative Konar-Multifunctional Occluder (MFO) to close Perimembranous Ventricular Septal Defects (PM-VSDs) in children.
Patients and methods: This retrospective study was applied on 28 pediatric patients who underwent transcatheter closure of hemodynamically significant PM-VSDs done in the Pediatric Cardiac Catheterization Unit in Cairo University Specialized Pediatric Hospital during the period from December 2020 to October 2022 using MFO device. Pre-procedural, procedural, post-procedural data were collected from patient files. Regular post procedural follow up was done for 12 months. Results: Twenty-eight patients underwent VSD closure using Konar-MFO. Median age and body weight of patients were 4.96 (2.6-14) years and 16 (12-60) kg respectively. The mean size of the left ventricular side of the VSD was 7.34 ± 1.61 mm on transthoracic echocardiography. The most used device size was 9/7 mm. The procedure was successful in 100% of cases. No major complications (device embolization, valve injury, complete heart block and thromboembolism) were reported.  Four (14.3%) cases had immediate small residual flow with 2 of them spontaneously closed at 6 months follow up. No neo-tricuspid or aortic valve insufficiency or cardiac dysrhythmia was detected during follow up. 
Conclusion:  Transcatheter closure of perimembranous VSD using Konar- MFO device is safe and effective in children with satisfactory short-term outcome.