Evaluation of Preoperative Application of Topical Testosterone Effect on The Result of Tabularized Incised Plate Repair Operation for Penile Hypospadias in Suez Canal University Hospitals

Background: For numerous years, the utilize of activating of hormones prior to surgical repair of a small sized phallus was deemed as a relatively common method. The beneficial influence of preoperative hormonal therapy remains contentious.
Objective: We aimed to evaluate the effect of topical testosterone application on result of tubularized incised plate (TIP) repair in distal hypospadias in Suez Canal University Hospitals.
Methods: A total of 96 male cases had distal hypospadias were recruited into the research and have been randomized to study or control group. Both groups were treated using the TIP repair. The study group patients received preoperative topical testosterone while the control group didn't, to evaluate the influence of topical testosterone application on result of TIP repair in distal hypospadias in Suez Canal University Hospitals.
Results: Mean glanular width was 14.83 mm prior to topical application of testosterone and increased to 16.9 mm with statistically significant variance (P below 0.05). There was statistically significant increase of glanular height with the use of topical testosterone. Mean glanular height increased from 9.2 mm to 13.1 mm with statistically significant variance (P below 0.05). there was a statistically insignificant variance among both groups according to late postoperative complications.
Conclusion:Our findings concluded that topical testosterone before TIP surgery for distal penile hypospadias had no significant impact on success rates or late complications but led to a higher rate of mild early postoperative complications.