Association between C Reactive Protein to Albumin Ratio and Presence and Severity of Coronary Artery Ectasia

Background: Localized or diffuse dilatation of the lumen of the coronary artery 1.5–2.0 times is known as coronary artery ectasia (CAE). In CAE, the C reactive protein (CRP)-to-albumin ratio (CAR) has been shown to be a valid and useful indicator of inflammation. Aim: This study aimed to correlate the CAR with the severity of isolated CAE.
Patients and methods: The eligible patients underwent selective coronary angiography (CA) followed by laboratory evaluation of quantified highly sensitive CRP, albumin, and CAR. The cases were divided into 3 groups according to CA: 30 with CAE, 30 with obstructive CAD, and 30 with normal CA. CAR was investigated in three different groups of patients and the relationship between CAR and the severity and presence of isolated CAE.
Results: CRP and CAR were significantly elevated in the CAE Group compared to other groups (p-value=0.001 and 0.007respectively). Additionally, CAR is negatively correlated with the severity of CAE (p value=0.013).
Conclusion: CAR was significantly correlated with the severity and presence of CAE. Therefore, these inflammatory markers are valuable for predicting and assessing the severity of ectasia.