(2025). Prognostic Value of Speckle Tracking Echocardiography on Left Ventricular Function after Percutaneous Coronary Stenting to Significant Proximal Left Anterior Descending Artery Stenosis. The Egyptian Journal of Hospital Medicine, 98(1), 1179-1187. doi: 10.21608/ejhm.2025.417869
. "Prognostic Value of Speckle Tracking Echocardiography on Left Ventricular Function after Percutaneous Coronary Stenting to Significant Proximal Left Anterior Descending Artery Stenosis". The Egyptian Journal of Hospital Medicine, 98, 1, 2025, 1179-1187. doi: 10.21608/ejhm.2025.417869
(2025). 'Prognostic Value of Speckle Tracking Echocardiography on Left Ventricular Function after Percutaneous Coronary Stenting to Significant Proximal Left Anterior Descending Artery Stenosis', The Egyptian Journal of Hospital Medicine, 98(1), pp. 1179-1187. doi: 10.21608/ejhm.2025.417869
Prognostic Value of Speckle Tracking Echocardiography on Left Ventricular Function after Percutaneous Coronary Stenting to Significant Proximal Left Anterior Descending Artery Stenosis. The Egyptian Journal of Hospital Medicine, 2025; 98(1): 1179-1187. doi: 10.21608/ejhm.2025.417869
Prognostic Value of Speckle Tracking Echocardiography on Left Ventricular Function after Percutaneous Coronary Stenting to Significant Proximal Left Anterior Descending Artery Stenosis
Background: Left ventricular systolic dysfunction (LVSD) and diabetes mellitus (DM) usually coexist, which raises patient morbidity and mortality. It is crucial to determine how isolated cases of a significant proximal stenosis of the left anterior descending artery in diabetic patients are affected by changes in the left ventricular function assessed by echocardiography after percutaneous coronary stenting. Objective: This study aimed to compare the early detection of changes in left ventricular systolic and diastolic performance in diabetic and non-diabetic patients using conventional and 2D speckle tracking echocardiography following successful percutaneous coronary intervention (PCI) with drug-eluting stenting of isolated stenosis of the proximal left anterior descending (LAD) artery. Patients and methods: A prospective cross-sectional study was conducted on 82 patients presenting with chest discomfort and myocardial ischemia at Al-Ahrar Teaching Hospital and Zagazig University Hospitals. Patients were categorized into two groups based on the occurrence of major adverse cardiovascular events (MACE) following percutaneous coronary intervention (PCI): Group I (MACE occurred) and Group II (MACE did not occur), stratified by diabetes status. All participants underwent electrocardiography (ECG) and echocardiography. Results: Pre-global longitudinal strain (GLS) and Delta GLS are significant predictor for MACE in diabetic and non-diabetic patients in univariate and multivariate logistic regression analysis. Conclusion: Patients with ischemic heart disease who had impaired systolic function improved significantly in diastolic dysfunction and all diastolic filling pattern measures after PCI.