Home Articles List Article Information
The Egyptian Journal of Hospital Medicine
Journal Archive
Volume Volume 99 (2025)
Volume Volume 98 (2025)
Volume Volume 100 (2025)
Volume Volume 97 (2024)
Volume Volume 96 (2024)
Volume Volume 95 (2024)
Volume Volume 94 (2024)
Volume Volume 93 (2023)
Volume Volume 92 (2023)
Volume Volume 91 (2023)
Volume Volume 90 (2023)
Volume Volume 89 (2022)
Volume Volume 88 (2022)
Volume Volume 87 (2022)
Volume Volume 86 (2022)
Volume Volume 85 (2021)
Volume Volume 84 (2021)
Volume Volume 83 (2021)
Volume Volume 82 (2021)
Volume Volume 81 (2020)
Volume Volume 80 (2020)
Volume Volume 79 (2020)
Volume Volume 78 (2020)
Volume Volume 77 (2019)
Volume Volume 76 (2019)
Volume Volume 75 (2019)
Volume Volume 74 (2019)
Volume Volume 73 (2018)
Volume Volume 72 (2018)
Volume Volume 71 (2018)
Volume Volume 70 (2018)
Volume Volume 69 (2017)
Volume Volume 68 (2017)
Volume Volume 67 (2017)
Volume Volume 66 (2017)
Volume Volume 65 (2016)
Volume Volume 64 (2016)
Volume Volume 63 (2016)
Volume Volume 62 (2016)
Volume Volume 61 (2015)
Volume Volume 60 (2015)
Volume Volume 59 (2015)
Volume Volume 58 (2015)
Volume Volume 57 (2014)
Volume Volume 56 (2014)
Volume Volume 55 (2014)
Volume Volume 54 (2014)
Volume Volume 53 (2013)
Volume Volume 52 (2013)
Volume Volume 51 (2013)
Volume Volume 50 (2013)
Volume Volume 49 (2012)
Volume Volume 48 (2012)
Volume Volume 47 (2012)
Volume Volume 46 (2012)
Volume Volume 45 (2011)
Volume Volume 44 (2011)
Volume Volume 43 (2011)
Volume Volume 42 (2011)
Volume Volume 41 (2010)
Volume Volume 40 (2010)
Volume Volume 39 (2010)
Volume Volume 38 (2010)
Volume Volume 37 (2009)
Volume Volume 36 (2009)
Volume Volume 35 (2009)
Volume Volume 34 (2009)
Volume Volume 33 (2008)
Volume Volume 32 (2008)
Volume Volume 31 (2008)
Volume Volume 30 (2008)
Volume Volume 29 (2007)
Volume Volume 28 (2007)
Volume Volume 27 (2007)
Volume Volume 26 (2007)
Volume Volume 25 (2006)
Volume Volume 24 (2006)
Volume Volume 23 (2006)
Volume Volume 22 (2006)
Volume Volume 21 (2005)
Volume Volume 20 (2005)
Volume Volume 19 (2005)
Volume Volume 18 (2005)
Volume Volume 17 (2004)
Volume Volume 16 (2004)
Volume Volume 15 (2004)
Volume Volume 14 (2004)
Volume Volume 13 (2003)
Volume Volume 12 (2003)
Volume Volume 11 (2003)
Volume Volume 10 (2003)
Volume Volume 9 (2002)
Volume Volume 8 (2002)
Volume Volume 7 (2002)
Volume Volume 6 (2002)
Volume Volume 5 (2001)
Volume Volume 4 (2001)
Volume Volume 3 (2001)
Volume Volume 2 (2001)
Volume Volume 1 (2000)
(2025). Efficacy of Non-Invasive Vagus Nerve Stimulation for Depression in Elderly. The Egyptian Journal of Hospital Medicine, 98(1), 897-904. doi: 10.21608/ejhm.2025.413757
. "Efficacy of Non-Invasive Vagus Nerve Stimulation for Depression in Elderly". The Egyptian Journal of Hospital Medicine, 98, 1, 2025, 897-904. doi: 10.21608/ejhm.2025.413757
(2025). 'Efficacy of Non-Invasive Vagus Nerve Stimulation for Depression in Elderly', The Egyptian Journal of Hospital Medicine, 98(1), pp. 897-904. doi: 10.21608/ejhm.2025.413757
Efficacy of Non-Invasive Vagus Nerve Stimulation for Depression in Elderly. The Egyptian Journal of Hospital Medicine, 2025; 98(1): 897-904. doi: 10.21608/ejhm.2025.413757

Efficacy of Non-Invasive Vagus Nerve Stimulation for Depression in Elderly

Article 130, Volume 98, Issue 1, January 2025, Page 897-904  XML PDF (431.18 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2025.413757
View on SCiNiTO View on SCiNiTO
Abstract
Background: Depression is one of the common mental illnesses affecting over 300 million subjects all over the world and has been considered a main cause of disability in recent years.
Objective: To investigate the effect of non-invasive vagus nerve stimulation (NVNS) for depression in elderly.
Patients and Methods Forty patients diagnosed with depression; their age 60-70 years old. They were selected according to inclusion criteria from Matareya Teaching Hospital and were divided into two groups equal in number Group < strong> A (Study group): Twenty (20) patients received vagus nerve stimulation as adjuvant to standard medical treatment and psychotherapy. Group < strong> B (Control group): Twenty (20) patients receivedstandard care for major depressive disorder (MDD) patients in the form of medical treatment and psychotherapy.
Results: There was statistically significant difference between two groups in the form of improvement the Hamilton Depression Rating Scale post treatment for group A and laboratory results of C-reactive protein (CRP), pro-inflammatory interleukin (IL)-6, IL-1, tumor necrosis factor-alpha (TNF-α), Serotonin post-treatment for group A in comparison to other group who did not receive non-invasive vagus nerve stimulation.
Conclusion: Use of NVNS for elderly patients with depression is an effective additional adjuvant intervention to alleviate symptoms and reduce the severity of the disease.
Keywords
Depression; NVNS; the HAMD; TNF-α; Interleukin
Statistics
Article View: 137
PDF Download: 199