Assessment of Mercury, Lead and Cadmium Levels among Children with Type 1 Diabetes in Suez Canal Region: Review Article

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The Egyptian Journal of Hospital Medicine

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	Assessment of Mercury, Lead and Cadmium Levels among Children with Type 1 Diabetes in Suez Canal Region: Review Article
Article 47, Volume 97, Issue 1, October 2024, Page 3738-3743 PDF (351.88 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2024.388695
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Abstract
Background: Type 1 diabetes mellitus (T1DM), a chronic illness requiring lifelong insulin treatment, is on the rise among children and adolescents globally. While, epidemiological studies on childhood T1D in Egypt are limited. Objective: This study aimed to elucidate potential links between environmental heavy metal exposure [mercury (Hg), lead (Pb), and cadmium (Cd)] and diabetes onset in children diagnosed with T1DM in Suez Canal region. Methods: In our search for information on T1DM, Mercury, Lead, we used Google Scholar, Science Direct, PubMed, and other internet databases. Additionally, the writers combed through relevant literature for references; however, they only included research that were either very recent or thorough, covering the years 2010–2023 Conclusion: While, the specific mechanisms by which heavy metals contribute to the disease are still being investigated, evidence suggests that these environmental toxins can play a significant role. Further research is crucial to understand the complex interactions between heavy metal exposure, oxidative stress, and autoimmune processes in the development and progression of T1D.
Keywords
Type 1 diabetes; Mercury; Lead; Cadmium


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