Serum Malondialdehyde (MDA) as Predictor for Severity of Coronary Artery Disease (CAD)

doi:10.21608/ejhm.2024.360963

Home Articles List Article Information

|
|
|
How to cite
RIS EndNote BibTeX APA MLA Harvard Vancouver
|
Share

The Egyptian Journal of Hospital Medicine

Articles in Press

Current Issue

Journal Archive

Volume 99 (2025)

Volume 98 (2025)

Volume 97 (2024)

Volume 96 (2024)

Volume 95 (2024)

Issue 1

Volume 94 (2024)

Volume 93 (2023)

Volume 92 (2023)

Volume 91 (2023)

Volume 90 (2023)

Volume 89 (2022)

Volume 88 (2022)

Volume 87 (2022)

Volume 86 (2022)

Volume 85 (2021)

Volume 84 (2021)

Volume 83 (2021)

Volume 82 (2021)

Volume 81 (2020)

Volume 80 (2020)

Volume 79 (2020)

Volume 78 (2020)

Volume 77 (2019)

Volume 76 (2019)

Volume 75 (2019)

Volume 74 (2019)

Volume 73 (2018)

Volume 72 (2018)

Volume 71 (2018)

Volume 70 (2018)

Volume 69 (2017)

Volume 68 (2017)

Volume 67 (2017)

Volume 66 (2017)

Volume 65 (2016)

Volume 64 (2016)

Volume 63 (2016)

Volume 62 (2016)

Volume 61 (2015)

Volume 60 (2015)

Volume 59 (2015)

Volume 58 (2015)

Volume 57 (2014)

Volume 56 (2014)

Volume 55 (2014)

Volume 54 (2014)

Volume 53 (2013)

Volume 52 (2013)

Volume 51 (2013)

Volume 50 (2013)

Volume 49 (2012)

Volume 48 (2012)

Volume 47 (2012)

Volume 46 (2012)

Volume 45 (2011)

Volume 44 (2011)

Volume 43 (2011)

Volume 42 (2011)

Volume 41 (2010)

Volume 40 (2010)

Volume 39 (2010)

Volume 38 (2010)

Volume 37 (2009)

Volume 36 (2009)

Volume 35 (2009)

Volume 34 (2009)

Volume 33 (2008)

Volume 32 (2008)

Volume 31 (2008)

Volume 30 (2008)

Volume 29 (2007)

Volume 28 (2007)

Volume 27 (2007)

Volume 26 (2007)

Volume 25 (2006)

Volume 24 (2006)

Volume 23 (2006)

Volume 22 (2006)

Volume 21 (2005)

Volume 20 (2005)

Volume 19 (2005)

Volume 18 (2005)

Volume 17 (2004)

Volume 16 (2004)

Volume 15 (2004)

Volume 14 (2004)

Volume 13 (2003)

Volume 12 (2003)

Volume 11 (2003)

Volume 10 (2003)

Volume 9 (2002)

Volume 8 (2002)

Volume 7 (2002)

Volume 6 (2002)

Volume 5 (2001)

Volume 4 (2001)

Volume 3 (2001)

Volume 2 (2001)

Volume 1 (2000)

	Serum Malondialdehyde (MDA) as Predictor for Severity of Coronary Artery Disease (CAD)
Article 140, Volume 95, Issue 1, April 2024, Page 2206-2211 PDF (596.24 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2024.360963
View on SCiNiTO
Abstract
Background: Coronary artery disease (CAD) occurs when the heart's myocardium receives an insufficient blood and oxygen supply. Objective: This study aimed to measure serum malondialdehyde (MDA) levels in CAD patients and examine their association with the disease's severity. Patients and Methods: This cross-sectional observational study involved 75 patients who underwent diagnostic coronary angiography to diagnose CAD. Patients were categorized into three groups based on their SYNTAX scores: the first group had mild CAD (SYNTAX score: ≤22), the second group had moderate CAD (SYNTAX score: 23-32), and the third group had severe CAD (SYNTAX score: ≥33). Results: The optimal MDA cutoff point for distinguishing between low and intermediate risk was >279.5 ng/ml, with a sensitivity of 83.3% and a specificity of 58.9%. The area under the curve (AUC) was 0.796, which was statistically significant (p=0.001). For differentiating between intermediate and high risk, the best MDA cutoff point was >342 ng/ml, with a sensitivity of 85.7% and a specificity of 91.7%. The AUC was 0.988, which was statistically significant (p < 0.001). Conclusion: Serum MDA levels could serve as a non-invasive biomarker to assess the severity of CAD, aligning with the findings from coronary angiography.
Keywords
Serum Malondialdehyde; Coronary Artery Disease; Disease Severity


Statistics Article View: 98 PDF Download: 158