Amhimmid, A., Gaafar, T., Hassan, A., Abd-El Aziz, M. (2023). Comparison between Two Different Doses of Intrathecal Dexamethasone Added to Bupivacaine for Post-operative Analgesia in Patients Undergoing Abdominal Hysterectomy. The Egyptian Journal of Hospital Medicine, 91(1), 5123-5129. doi: 10.21608/ejhm.2023.303641
Ahmed Omar Abdulqadir Amhimmid; Tarek Yousef Gaafar; Ayman Abdelsalam Hassan; Mohamed Ali Abd-El Aziz. "Comparison between Two Different Doses of Intrathecal Dexamethasone Added to Bupivacaine for Post-operative Analgesia in Patients Undergoing Abdominal Hysterectomy". The Egyptian Journal of Hospital Medicine, 91, 1, 2023, 5123-5129. doi: 10.21608/ejhm.2023.303641
Amhimmid, A., Gaafar, T., Hassan, A., Abd-El Aziz, M. (2023). 'Comparison between Two Different Doses of Intrathecal Dexamethasone Added to Bupivacaine for Post-operative Analgesia in Patients Undergoing Abdominal Hysterectomy', The Egyptian Journal of Hospital Medicine, 91(1), pp. 5123-5129. doi: 10.21608/ejhm.2023.303641
Amhimmid, A., Gaafar, T., Hassan, A., Abd-El Aziz, M. Comparison between Two Different Doses of Intrathecal Dexamethasone Added to Bupivacaine for Post-operative Analgesia in Patients Undergoing Abdominal Hysterectomy. The Egyptian Journal of Hospital Medicine, 2023; 91(1): 5123-5129. doi: 10.21608/ejhm.2023.303641
Comparison between Two Different Doses of Intrathecal Dexamethasone Added to Bupivacaine for Post-operative Analgesia in Patients Undergoing Abdominal Hysterectomy
Background: Insufficient surgical pain management can hinder healing, raise healthcare expenses, and decrease patient satisfaction. According to some investigations, spinal bupivacaine-dexamethasone showed analgesic effects that were nearly as potent as those of bupivacaine-fentanyl while also having opioid-sparing and antiemetic properties. The optimal spinal dexamethasone dosage for postoperative analgesia has not yet been established. It was therefore required to conduct a study looking at the effectiveness and safe amount of spinal dexamethasone for postoperative analgesia in patients having abdominal hysterectomy. Aim: Optimizing post-operative analgesia using two different doses of intrathecal dexamethasone added to bupivacaine in patients undergoing abdominal hysterectomy. Patients and methods: This study was conducted on patients who underwent elective abdominal hysterectomy at Zagazig University Hospitals' Department of Anaesthesia, Intensive Care, and Pain Management. The patients were divided into 3 groups (43 subjects each): Group C (Control group) received intrathecal bupivacaine 0.5% 4 cc plus 1 cc normal saline, group D2: received intrathecal bupivacaine 0.5% 4 cc plus 2 mg dexamethasone in 1cc volume and group D4 received intrathecal bupivacaine 0.5% 4 cc plus 4 mg dexamethasone in 1cc volume. Results:In terms of post-operative discomfort, there were statistically significant differences between groups C and D4 at various follow-up intervals. Also, between groups D2 and D4 from 0 to 12 hours after surgery. Conclusion: In women having abdominal hysterectomy surgery, intrathecal dexamethasone 4 mg combined with bupivacaine increased the intensity and duration of post-operative analgesia without causing any negative side effects.