Ali, A., El-Aaser, N., Abaza, K., Mohamed, A. (2023). Study of Dexmedetomidine versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia after Cesarean Delivery. The Egyptian Journal of Hospital Medicine, 91(1), 4765-4771. doi: 10.21608/ejhm.2023.299502
Abdullah Abobakr Ali; Neveen Mahmoud El-Aaser; Kamelia Ahmed Abaza; Abdalla Mohamed Goda Mohamed. "Study of Dexmedetomidine versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia after Cesarean Delivery". The Egyptian Journal of Hospital Medicine, 91, 1, 2023, 4765-4771. doi: 10.21608/ejhm.2023.299502
Ali, A., El-Aaser, N., Abaza, K., Mohamed, A. (2023). 'Study of Dexmedetomidine versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia after Cesarean Delivery', The Egyptian Journal of Hospital Medicine, 91(1), pp. 4765-4771. doi: 10.21608/ejhm.2023.299502
Ali, A., El-Aaser, N., Abaza, K., Mohamed, A. Study of Dexmedetomidine versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia after Cesarean Delivery. The Egyptian Journal of Hospital Medicine, 2023; 91(1): 4765-4771. doi: 10.21608/ejhm.2023.299502
Study of Dexmedetomidine versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia after Cesarean Delivery
Background: Dexmedetomidine's potential to increase blockade duration has piqued the interest of researchers as a local anaesthetic adjuvant in recent years. As an opioid analgesic, fentanyl is highly effective. Objective: Improving postoperative analgesia after Cesarean delivery using dexmedetomidine or fentanyl as additives to bupivacaine for transversus abdominis plane block with ultrasonography guidance. Patients and Methods: One hundred and twenty cases were randomly divided into two equal groups each included 60 cases. Group D received ultrasound guidedtransversus abdominis plane (TAP) block using dexmedetomidine 1 microgram/kg + 40 ml bupivacaine 0.25%, and the volume was divided equally and given bilaterally. Group F received ultrasound guided TAP block using fentanyl 1 microgram/kg + 40 ml bupivacaine 0.25%, and the volume was divided equally and given bilaterally. Results: Group D had lower mean arterial pressure as well as heart rate than group F at 4, 8, 12, 18, and 24 hours post-operative. Group D had a significantly longer time to first analgesia compared to group F. Group D had significantly reduced total analgesic intake compared to group F over a 24-hour period. Rescue analgesics were needed by a greater percentage of patients in group F than in group D after 6, 12, and 24 hours. A statistically significant difference was seen between the two groups after 20 and 24 hours on the VAS, with group D scoring lower than group F. Conclusion: Dexmedetomidine was more effective than fentanyl in providing postoperative analgesia with bupivacaine for transversus abdominis plane block with ultrasonography guidance following caesarean section.
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