Lafta, K., Abdullah, M., Al Khaqani, F., Jaber, A. (2023). The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital. The Egyptian Journal of Hospital Medicine, 91(1), 4707-4711. doi: 10.21608/ejhm.2023.299487
Kamal Breesam Lafta; Muntadher Abdulkareem Abdullah; Fatih A. Al Khaqani; Akeel M. Jaber. "The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital". The Egyptian Journal of Hospital Medicine, 91, 1, 2023, 4707-4711. doi: 10.21608/ejhm.2023.299487
Lafta, K., Abdullah, M., Al Khaqani, F., Jaber, A. (2023). 'The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital', The Egyptian Journal of Hospital Medicine, 91(1), pp. 4707-4711. doi: 10.21608/ejhm.2023.299487
Lafta, K., Abdullah, M., Al Khaqani, F., Jaber, A. The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital. The Egyptian Journal of Hospital Medicine, 2023; 91(1): 4707-4711. doi: 10.21608/ejhm.2023.299487
The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital
Background: Osteoporosis (OP) has become an increasingly recognized complication among patients with chronic liver disease (CLD). Objective: This study aimedto determine the prevalence of osteoporosis among patients with CLD and to identify the risk factors associated with osteoporosis in these patients. Materials and Methods: One hundred patients who visited Basrah Gastroenterology and Hepatology Hospital between February 2020 and December 2021 with assessed osteoporosis. Using dual energy X-ray absorptiometry (DEXA), bone density was evaluated. The severity of liver disease, smoking, alcohol use, demographic, biochemical characteristics were all taken while assessing the risk factors for osteoporosis. Results: Of the 100 patients (male/female: 44%/56%, mean age (46 ± 11.5), 50% had CLD diagnoses, 50% did not. Of the 50 patients with CLD,20 patients had OP(40%),while four patients (8%) of the 50 patients without CLD had OP. Twenty-four (24%) of the total patients who undertook the DEXA study showed OP, while seventy-six (76%) did not. Twenty of the twenty-four individuals with OP had CLD (84%) while just four (16%) did not. Child-Pugh A made up 26% of CLD patients, Child-Pugh B 30%, while Child-Pugh C 44%. In this study, osteoporosis and osteopenia were present at rates of 24% and 31% respectively. OP and CLD appeared to be related in a very substantial way (p 0.001). CLD was identified as an independent predictor of OP by multivariate logistic regression analysis (OR (95% CI):9.09(2.18-37.93), p=0.0 Conclusion: It was determined that OP and CLD are significantly correlated. People with CLD were more likely to develop OP. As a result, routine follow-up of these individuals may require biochemical and bone mineral density (BMD) monitoring.
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