Abdel Mawla, T., Abdel Hameed, A., Zaky, S., El Khashab, K. (2019). Fragmented QRS and Ventricular Arrhythmias in Coroary Artery Disease Patients. The Egyptian Journal of Hospital Medicine, 75(1), 2048-2053. doi: 10.21608/ejhm.2019.29713
Tamer Sayed Mohamed Abdel Mawla; Asmaa Mizar Abdel Hameed; Sherif Hamed Zaky; Khaled Ahmed El Khashab. "Fragmented QRS and Ventricular Arrhythmias in Coroary Artery Disease Patients". The Egyptian Journal of Hospital Medicine, 75, 1, 2019, 2048-2053. doi: 10.21608/ejhm.2019.29713
Abdel Mawla, T., Abdel Hameed, A., Zaky, S., El Khashab, K. (2019). 'Fragmented QRS and Ventricular Arrhythmias in Coroary Artery Disease Patients', The Egyptian Journal of Hospital Medicine, 75(1), pp. 2048-2053. doi: 10.21608/ejhm.2019.29713
Abdel Mawla, T., Abdel Hameed, A., Zaky, S., El Khashab, K. Fragmented QRS and Ventricular Arrhythmias in Coroary Artery Disease Patients. The Egyptian Journal of Hospital Medicine, 2019; 75(1): 2048-2053. doi: 10.21608/ejhm.2019.29713
Fragmented QRS and Ventricular Arrhythmias in Coroary Artery Disease Patients
Background: Fragmented QRS represents myocardial scar and will be associated with ventricular dysfunction and occurrence of congestive heart failure. In CAD, fQRS represents prior occurrence of myocardial infarction and will have a risk of subsequent occurrence of ischemic events. Objective: in our study we aimed to determine whether fragmented QRS (fQRS) is associated with increased incidence of ventricular arrhythmias in patients with coronary artery disease (CAD) or not . Patients and Methods: one hundred patients with CAD were included. Patients were divided into two groups according to presence or absence of fQRS on admission ECG. Group 1 (n=50) was defined as a fQRS (+ve) and group 2 (n=50) was defined as a fQRS (-ve). All patients were subjected to full history taking, complete physical examination, ECG, echocardiography and laboratory investigations. Results: There was higher incidence of fQRS in hypertensive patients (72%). FQRS was found to be associated with increased incidence of ventricular arrhythmias, 52% in group 1 versus 24% in group II. EF % was significantly lower in group I than in group 2 with p value 0.03. Fragmented QRS was an independent predictor of all-cause mortality with p value 0.02. Conclusion: fQRS on the resting surface electrocardiogram is a simple, fast and inexpensive modality of noninvasive investigation for evaluation of CAD patients. Patients who have known CAD present with a fQRS have an increased rate of ventricular tachyarrhythmias, death risk, and low ejection fraction.
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