Overview about Correlation between Heart Failure and Diabetes Mellitus: Review Article

Mabrouk, Azeezah Rabeea Raghib; Elmaghawry, Laila Mohamad; Shereef, Ahmed Shawky; El-Shetry, Mohamed Saad

doi:10.21608/ejhm.2023.296743

Overview about Correlation between Heart Failure and Diabetes Mellitus: Review Article

Document Type : Original Article

Authors

10.21608/ejhm.2023.296743

Abstract

Background: Myocardial shape and function can be altered by diabetes alone, without the presence of other risk factors like hypertension, ischemic heart disease and a condition known as diabetic cardiomyopathy (DCM). Diabetes is associated with a wide range of metabolic disturbances, some of which have been linked to the emergence of DCM. Some examples are elevated blood sugar levels, abnormal lipid profiles, an increase in the release of free fatty acids (FFAs), and insulin resistance.
Objective: Review of literature about correlation between heart failure and diabetes mellitus.
Methods: Heart failure and diabetes mellitus were searched for on Science Direct, Google Scholar, and PubMed. The authors also reviewed the relevant literature, nonetheless, only the most recent or exhaustive analysis was included, covering the time span from September 2010 to November 2022. There are no translation resources available, thus non-English documents are out. Unpublished articles, oral presentations, conference abstracts, and dissertations were not included because they were not considered to be part of major scientific projects.
Conclusion: There is a lack of understanding of the molecular underpinnings and pathophysiology of heart failure in diabetic people. The incidence, prevalence, and outlook for heart failure in diabetic individuals have been proven by certain clinical and epidemiologic data. In recent decades, diabetic heart disease has emerged as a major contributor to the mortality rate among diabetics.

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