Background: Patients with diabetes and systemic lupus erythematosus (SLE) frequently have sleep disruption. Unfortunately, there is still a lack of knowledge about the relationship between the incidence of sleep disorders in SLE and the causes of these disorders. Objectives: To study the sleep breathing disorders among diabetic patients with systemic lupus erythematosus (SLE) and associated relationship with both disease severity and activity. Patients and Methods: Thirty diabetic patients with SLE and thirty apparent healthy control subjects were enrolled in this work. For all patients, full medical histories, in-depth clinical exams, Epworth sleepiness ratings (ESS), laboratory evaluations, and complete overnight polysomnography were done. Results:Diabetic patients with SLE have a lower significant total sleep time (TST), sleep onset, sleep efficiency (%), percent of sleep in supine than controls (p < 0.001 for all). However, diabetic patients with SLE have a higher significant Spon Arousal index, number of awaking/hour, low limitation index and apnea/hypopnea index in supine than controls (p < 0.001 for all). Diabetic patients with SLE have a higher significant periodic leg movements during sleep (PLMS) sequence, apnea/hypopnea index (AHI), oxygen desaturation events (OD), percent of snoring time in TST, percent of rapid eye movement sleep (REM) in TST, total AHI in non-rapid eye movement sleep (NREM), total AHI in REM, ESR, CRP, uric acid and FBS, HBA1c% than controls (p < 0.001 for all). However, diabetic patients with SLE have a lower significant average oxygen saturation % and lowest oxygen saturation (%) than controls (p < 0.001 for all). Conclusion: Sleep breathing problems are frequently seen in people with systemic lupus erythematosus and diabetes. These patients' disease activity and poor glycemic management may be significant contributors to their sleep disruption.
Abdel Tawab, A. M., algendy, D. S., Salman, M. M. A. E. R., & Sharaf, M. M. (2023). Prevalence of Sleep Disorders Among Diabetic Patients with Systemic Lupus Erythematosus in Menoufia University Hospital. The Egyptian Journal of Hospital Medicine, 91(1), 3995-4000. doi: 10.21608/ejhm.2023.294166
MLA
Asmaa Metwally Abdel Tawab; Doaa Salah algendy; Maha Mohamed Abd El Raof Salman; Marwa Mohammad Sharaf. "Prevalence of Sleep Disorders Among Diabetic Patients with Systemic Lupus Erythematosus in Menoufia University Hospital", The Egyptian Journal of Hospital Medicine, 91, 1, 2023, 3995-4000. doi: 10.21608/ejhm.2023.294166
HARVARD
Abdel Tawab, A. M., algendy, D. S., Salman, M. M. A. E. R., Sharaf, M. M. (2023). 'Prevalence of Sleep Disorders Among Diabetic Patients with Systemic Lupus Erythematosus in Menoufia University Hospital', The Egyptian Journal of Hospital Medicine, 91(1), pp. 3995-4000. doi: 10.21608/ejhm.2023.294166
VANCOUVER
Abdel Tawab, A. M., algendy, D. S., Salman, M. M. A. E. R., Sharaf, M. M. Prevalence of Sleep Disorders Among Diabetic Patients with Systemic Lupus Erythematosus in Menoufia University Hospital. The Egyptian Journal of Hospital Medicine, 2023; 91(1): 3995-4000. doi: 10.21608/ejhm.2023.294166
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