Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men

Document Type : Original Article

Authors

Department of urology,faculty of medicine.Benha University, Benha,Egypt

Abstract

Background: Primary premature ejaculation (PE) can be effectively treated with sildenafil citrate, according to recent research. This study evaluated sildenafil citrate efficacy in primary PE treatment, considering the female perspective. Methods: Sixty sexually active men diagnosed with primary PE were split into two groups randomly and followed for 6 months. Group A received 50 mg of sildenafil citrate one hour before sexual activity in accordance with standard dosing guidelines (not fewer than once a week), while Group B received paroxetine 20 mg daily for six months. At baseline, 3 months, and 6 months following therapy, the intravaginal ejaculatory latency time (IELT), PE grade, intercourse satisfying score (ISS), intercourse frequency, and drug-associated side effects were noted.
Results: Both groups showed significant improvements in all measurements following 3 or 6 months of therapy, with no critical changes between two time points. However, sildenafil citrate was found to be significantly more effective than paroxetine in improving all parameters at both 3 and 6 months (P = 0.001).
Conclusion: Sildenafil citrate is a highly beneficial treatment for primary PE and is more effective than paroxetine.
 

Keywords

The Egyptian Journal of Hospital Medicine
Volume 90, Issue 2
January 2023
Pages 3620-3624

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