Abdel Fattah, A., Elmohamady, B., El Hamshary, S., Abu El-Nasr, H. (2023). Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men. The Egyptian Journal of Hospital Medicine, 90(2), 3620-3624. doi: 10.21608/ejhm.2023.292762
Ahmed Abou Elezz Abdel Fattah; Basheer Nagy Elmohamady; Salah A. El Hamshary; Hosam Abu El-Nasr. "Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men". The Egyptian Journal of Hospital Medicine, 90, 2, 2023, 3620-3624. doi: 10.21608/ejhm.2023.292762
Abdel Fattah, A., Elmohamady, B., El Hamshary, S., Abu El-Nasr, H. (2023). 'Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men', The Egyptian Journal of Hospital Medicine, 90(2), pp. 3620-3624. doi: 10.21608/ejhm.2023.292762
Abdel Fattah, A., Elmohamady, B., El Hamshary, S., Abu El-Nasr, H. Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men. The Egyptian Journal of Hospital Medicine, 2023; 90(2): 3620-3624. doi: 10.21608/ejhm.2023.292762
Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men
Department of urology,faculty of medicine.Benha University, Benha,Egypt
Abstract
Background: Primary premature ejaculation (PE) can be effectively treated with sildenafil citrate, according to recent research. This study evaluated sildenafil citrate efficacy in primary PE treatment, considering the female perspective. Methods: Sixty sexually active men diagnosed with primary PE were split into two groups randomly and followed for 6 months. Group A received 50 mg of sildenafil citrate one hour before sexual activity in accordance with standard dosing guidelines (not fewer than once a week), while Group B received paroxetine 20 mg daily for six months. At baseline, 3 months, and 6 months following therapy, the intravaginal ejaculatory latency time (IELT), PE grade, intercourse satisfying score (ISS), intercourse frequency, and drug-associated side effects were noted. Results: Both groups showed significant improvements in all measurements following 3 or 6 months of therapy, with no critical changes between two time points. However, sildenafil citrate was found to be significantly more effective than paroxetine in improving all parameters at both 3 and 6 months (P = 0.001). Conclusion: Sildenafil citrate is a highly beneficial treatment for primary PE and is more effective than paroxetine.